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First received: October 16, 2022

Clinical Trial: Immunogenicity Assessment of Subjects Receiving Rabies Post-exposure Prophylaxis in Cambodia

Study Status: Completed

Recruit Status: Completed

Condition: Rabies Post-exposure Prophylaxis

Study Type: Observational


Official Title: Immunogenicity Assessment of Subjects Receiving Rabies Post-exposure Prophylaxis in Cambodia

Brief Summary: A rabies virus neutralizing antibody (RVNA) concentration ? 0.5 IU/ml at 14 days after immunization is considered a proxy for protection in vaccine efficacy studies. Abridged and dose-sparing vaccination regimens increase accessibility and reduce both direct and indirect costs, especially in resource-constrained countries where RABV prevalence is highest. Several efficacy studies evaluated safety and immunogenicity of abridged regimens in healthy adult volunteers using either four-site intradermal (ID) or…

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