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First received: December 7, 2022

Clinical Trial: Comparing the Gastric Transit of Commercial Milk and A2 Milk

Study Status: Active, not recruiting

Recruit Status: Active, not recruiting

Condition: Lactose Intolerance, Adult Type

Study Type: Interventional


Official Title: Comparing the Gastric Transit of Commercial Milk Containing A1 Beta-casein and A2 Milk Containing Only A2 Beta-casein Using Magnetic Resonance Imaging (MRI)

Brief Summary: Cow's milk contains two types of ?-casein: A1 and A2. The ?-opioid peptide BCM-7 is released from A1 but not from A2. BCM-7 is associated with slower gastrointestinal transit and hence increased gastrointestinal transit times. Lactose maldigesters reported an increase in abdominal pain due to consumption of milk containing A1 beta-casein as compared to milk containing only A2 beta-casein. The hypothesis of this study is that the differential abdominal pain is due to the differential gastric transit. This is a…

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