Clinical Trial: Prospective Study of Short Course Radiation Therapy Followed by Neoadjuvant Chemotherapy and Surgery in Locally Advanced Rectal Cancer
Study Status: Completed
Recruit Status: Completed
Condition: Locally Advanced Rectal Carcinoma
Study Type: Interventional
Official Title: Prospective Phase II Study of Hypofractionated Short Course Radiation Therapy Followed by Neoadjuvant Chemotherapy and Surgery in Locally Advanced Rectal Cancer
Brief Summary:
The goal of this clinical trial is to investigate total neoadjuvant therapy (TNT) using short course radiation therapy (SCRT) followed by full course of chemotherapy then surgery in locally advanced rectal cancer. The main questions it aims to answer are:Is total neoadjuvant treatment in this design safe & tolerable?Impact of this design on treatment related outcomes in terms of pathological and clinical responses.
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