Clinical Trial: Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C
Study Status: Completed
Recruit Status: Completed
Condition:
Burns
Ascorbic Acid Deficiency
Burn Shock
Burn Degree Second
Burn Degree Third
Study Type: Observational
Official Title: High Dose Intravenous Versus Low Dose Oral Vitamin C in Burn Care: Potential Protective Effects in the Severely Burned: A Retrospective Cohort Study
Brief Summary:
Burn injury is marked by a large release of inflammatory mediators which disrupt the normal capillary barrier and cause a rapid shift of intravascular fluid into interstitial spaces, ultimately leading to shock and death. As such, adequate fluid management and resuscitation is critical for burn patients to prevent further cellular injury. Technologies and medical options such as cardiac output monitoring along with early tube feeding and vitamin C administration have developed slowly over the years. Effective…
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