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First received: October 26, 2022

Clinical Trial: Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C

Study Status: Completed

Recruit Status: Completed

Condition: Burns
Ascorbic Acid Deficiency
Burn Shock
Burn Degree Second
Burn Degree Third

Study Type: Observational


Official Title: High Dose Intravenous Versus Low Dose Oral Vitamin C in Burn Care: Potential Protective Effects in the Severely Burned: A Retrospective Cohort Study

Brief Summary: Burn injury is marked by a large release of inflammatory mediators which disrupt the normal capillary barrier and cause a rapid shift of intravascular fluid into interstitial spaces, ultimately leading to shock and death. As such, adequate fluid management and resuscitation is critical for burn patients to prevent further cellular injury. Technologies and medical options such as cardiac output monitoring along with early tube feeding and vitamin C administration have developed slowly over the years. Effective…

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