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First received: January 09, 2023

Clinical Trial: Effect of Dapagliflozin on Microvascular Function in Women With Symptoms of Coronary Artery Disease

Study Status: Completed

Recruit Status: RECRUITING

Condition: Myocardial Ischemia

Study Type: INTERVENTIONAL


Official Title: A Single-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate Microvascular Disease After 12 Weeks of Therapy With Sodium-glucose Co-transporter 2 Inhibitor Compared to Placebo in Sy

Brief Summary: The goal of this clinical trial is to test the effects of a drug (in the drug class called sodium-glucose cotransporter 2 inhibitors) in women who have symptoms of ischemic heart disease.The main questions the study aims to answer are:Does blood flow in the heart improve with study drug?Participants will be randomly assigned to a 12-week course of the study drug, dapagliflozin 10mg, or placebo.Blood flow in the heart will be assessed using stress cardiac magnetic resonance imaging at baseline and 12 weeks.The…

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