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First received: January 09, 2023

Clinical Trial: Evaluation of Hydroxychloroquine to Prevent CIPN

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Breast Cancer

Study Type: INTERVENTIONAL


Official Title: Phase 2, Single Center, Single Arm Study to Evaluate the Decrease in CIPN With the Addition of Hydroxychloroquine to Chemotherapy in Patients With Early Stage (1-3) Breast Cancer and Gynecological Can

Brief Summary: The study is being done to research if hydroxychloroquine can prevent chemotherapy induced peripheral neuropathy.Certain chemotherapy drugs, like paclitaxel, are known to cause neuropathy which can impact quality of life.Currently, there are no options for preventing peripheral neuropathy.In addition, there are no useful methods to assess peripheral nerve damage.This study will also explore using a study MRI of patients' feet prior to starting chemotherapy and after they have completed chemotherapy to see if…

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