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First received: December 16, 2022

Clinical Trial: A Study of the Effects of Oxytocin in Adults With Obesity and Binge-eating Disorder

Study Status: Completed

Recruit Status: RECRUITING

Condition: Binge-eating Disorder

Study Type: INTERVENTIONAL


Official Title: A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effects of Intranasal Oxytocin in Adults With Obesity and Binge- Eating Disorder

Brief Summary: This study evaluates the impact of intranasal oxytocin vs placebo in patients with obesity and binge eating disorder with obesity.We hypothesize that 8 weeks of intranasal oxytocin vs placebo will improve clinical outcomes [weight loss, reduction in bingeing frequency], and have a satisfactory safety and tolerability profile.We will also explore the predictive value of changes in homeostatic appetite, reward sensitivity, and impulse control, the identified underlying mediators, as assessed 4 weeks into the…

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