Clinical Trial: Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections
Study Status: Completed
Recruit Status: RECRUITING
Condition: Gram-negative Bacterial Infections
Study Type: INTERVENTIONAL
Official Title: A PHASE 2A MULTICENTER, OBSERVER-BLINDED, RANDOMIZED 2 ARM STUDY TO INVESTIGATE PHARMACOKINETICS, SAFETY, TOLERABILITY AND EFFICACY OF INTRAVENOUS AZTREONAM-AVIBACTAM ± METRONIDAZOLE COMPARED TO BEST
Brief Summary:
The purpose of this study is to evaluate how Aztreonam (ATM) and Avibactam (AVI) are processed in pediatric participants.This study also aims to understand participant safety and effects in pediatric participants.The study is seeking participants who are:9 months to less than 18 years of ageHospitalizedSuspected/known to have a gram-negative infectionReceiving intravenous (iv, given directly into a vein) antibioticsBeing treated for complicated infections of various body parts that includes the abdomen,…
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