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First received: December 05, 2022

Clinical Trial: Udall Project 2 Aim 2A&C

Study Status: Completed

Recruit Status: RECRUITING

Condition: Parkinson Disease

Study Type: OBSERVATIONAL


Official Title: Mechanisms and Effects of Pallidal Deep Brain Stimulation on Levodopa Resistant Motor Signs in Parkinson's Disease; Udall Project 2 Aim 2A&C

Brief Summary: This protocol will leverage the novel (on-label, FDA-approved) local field potential measuring capability of the Medtronic Percept™ PC DBS system to study the effects of globus pallidus internus and globus pallidus externus (GPi, GPe) DBS on: the wash-out and wash-in dynamics of motor behavior and local field potentials (LFPs) and correlations between fluctuations in gait and LFPs during activities of daily living (recorded over 4 weeks).These experiments will elucidate the relationships between GP LFPs…

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