Clinical Trial: Inhaled Nitric Oxide for Microvascular Dysfunction in Traumatic Brain Injury
Study Status: NOT_YET_RECRUITING
Recruit Status: NOT_YET_RECRUITING
Condition: Traumatic Brain Injury
Study Type: INTERVENTIONAL
Official Title: Inhaled Nitric Oxide for Microvascular Dysfunction in Traumatic Brain Injury
Brief Summary:
Traumatic brain injury (TBI) causes acute deficits in cerebral perfusion which may lead to secondary injury and worse outcomes.Inhaled nitric oxide (iNO) is a vasodilator that increases cerebral blood flow and is clinically used for hypoxic respiratory failure in neonates and adults.The investigators will perform a randomized controlled trial of iNO treatment in TBI patients acutely after injury.The investigators will then assess perfusion changes with optic neuromonitoring, blood biomarkers, and 6 month clinical…
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