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First received: December 27, 2022

Clinical Trial: Pharmacological Agents for Chronic Spinal Cord Injury (SCI)

Study Status: Completed

Recruit Status: RECRUITING

Condition: Spinal Cord Injuries

Study Type: INTERVENTIONAL


Official Title: The Role of Pharmacological Agents in Restoring Neuronal Excitability After Chronic Spinal Cord Injury (SCI)

Brief Summary: The purpose of this study is to investigate the short-term effects of 3 approved FDA drugs (cyproheptadine (CPH), carbidopa-levodopa (CD-LD), and atomoxetine (ATX)) on motor responses when delivered in combination with hand training exercises in people with chronic spinal cord injury.The goal is to learn how to better strengthen connections between the brain and spinal cord after spinal cord injury, and if this connection is improved by one(or more) of the drugs.Multiple aspects of nerve transmission and muscle…

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