Clinical Trial: High Dose Buprenorphine (BUP) Induction in the Emergency Department (ED)
Study Status: Completed
Recruit Status: RECRUITING
Condition: Opioid Use Disorder
Study Type: INTERVENTIONAL
Official Title: Safety and Efficacy of High Dose Buprenorphine Induction in Fentanyl Positive Emergency Department Patients
Brief Summary:
This project, involving two distinct clinical trials, tests whether induction to a higher than currently recommended buprenorphine (BUP) induction dose is safe and can improve the proportion of patients who engage in comprehensive addiction services within 7-day of induction.Trial 1 is a head-to-head comparison of the safety, tolerability and feasibility of high dose BUP induction (32 mg).The study involves two cohorts, (1) a 12mg cohort (standard) to determine baseline data and (2) a 32 mg (high dose) cohort.If…
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