Clinical Trial: Precision Medicine for the Prediction of Treatment (PROMPT) Response (PROMPT)
Study Status: Completed
Recruit Status: RECRUITING
Condition: Major Depressive Disorder
Study Type: OBSERVATIONAL
Official Title: Toward PrecisiOn Medicine for the Prediction of Treatment Response in Major Depressive Disorder Through Stratification of Combined Clinical And-omics Signatures (PROMPT)
Brief Summary:
Major depressive disorder (MDD) is the most common psychiatric disease worldwide with a huge socio-economic impact.Pharmacotherapy represents the first-line treatment choice; however, only about one third of patients respond to the first trial and about 30% are classified as treatment-resistant depression (TRD).TRD is associated with specific clinical features and genetic/gene expression signatures.To date, single sets of markers have shown limited power in response prediction.The aim of this project is the…
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