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First received: August 30, 2022

Clinical Trial: Precision Medicine for the Prediction of Treatment (PROMPT) Response (PROMPT)

Study Status: Completed

Recruit Status: RECRUITING

Condition: Major Depressive Disorder

Study Type: OBSERVATIONAL


Official Title: Toward PrecisiOn Medicine for the Prediction of Treatment Response in Major Depressive Disorder Through Stratification of Combined Clinical And-omics Signatures (PROMPT)

Brief Summary: Major depressive disorder (MDD) is the most common psychiatric disease worldwide with a huge socio-economic impact.Pharmacotherapy represents the first-line treatment choice; however, only about one third of patients respond to the first trial and about 30% are classified as treatment-resistant depression (TRD).TRD is associated with specific clinical features and genetic/gene expression signatures.To date, single sets of markers have shown limited power in response prediction.The aim of this project is the…

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