Clinical Trial: Risk of Failed Epidural in Patients With and Without Chronic Pain and Opioid Use
Study Status: COMPLETED
Recruit Status: COMPLETED
Condition: Chronic Pain
Study Type: OBSERVATIONAL
Official Title: Cohort Study: Risk of Failed Epidural in Patients With and Without Chronic Pain and Opioid Use Undergoing Laparotomy
Brief Summary:
Patients with chronic pain syndrome (CPS) may develop central sensitization wich may lead to increased pain intensity and lower pain threshold sometimes to the extend of hyperalgesia and allodynia.Furthermore, patients with daily use of opioids may develop opioid tolerance, and to a lesser extent opioid induced hyperalgesia.These factors may lead to a higher pain intensity in the perioperative setting resulting in the observed increased opioid dosage needed to treat the acute pain.Furthermore opioid titration may…
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