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First received: March 28, 2025

Clinical Trial: Plant-Based Foods and (Poly)Phenol Supplementation in Gut Microbiota Modulation, Body Weight, and Cardiometabolic Risk

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Obesity and Overweight

Study Type: INTERVENTIONAL


Official Title: Exploring the Role of Native Plant-Based Foods and (Poly)Phenol Supplementation in Modifying Gut-Microbiota Metabolism: A Strategy for Reducing Body Weight and Cardiometabolic Risk

Brief Summary: This single-blind, randomized controlled trial aims to evaluate the effects of increased dietary polyphenol intake-either through a healthy plant-based diet (PBD) or supplementation-on body weight and cardiometabolic risk factors in adults with overweight or obesity.A total of 99 participants (aged 25-45 years, BMI 25-35 kg/m²) with cardiovascular risk factors will be recruited from local health centers and randomly assigned (1:1:1) to one of three intervention groups for 12 weeks: (1) a healthy PBD rich in…

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