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First received: June 30, 2026

Clinical Trial: Acute Effects of Cervical Manual Therapy on Eye Blood Flow

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Chronic Mechanical Neck Pain

Study Type: INTERVENTIONAL


Official Title: Acute Effects of Cervical Manual Therapy on Retinal and Choroidal Perfusion Assessed by Optical Coherence Tomography Angiography: A Prospective Randomized Sham-Controlled Trial

Brief Summary: This study evaluates the acute effects of cervical manual therapy on retinal and choroidal microvascular perfusion using optical coherence tomography angiography (OCTA). In this prospective randomized sham-controlled trial, 100 patients with chronic mechanical neck pain were randomly assigned to receive either cervical high-velocity low-amplitude manipulation combined with Maitland mobilization (manual therapy group) or sham treatment. Bilateral OCTA examinations were performed at baseline and at 15, 30, 60, and…

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