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First received: June 04, 2026

Clinical Trial: A Clinical Trial to Assess the Pharmacokinetic Profile of Propylene Glycol (PG) in Healthy Adults Following PG Exposure

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Healthy
Pharmacokinetic Profile
Propylene Glycol

Study Type: INTERVENTIONAL


Official Title: An Open-label, Dose-escalation Clinical Trial to Assess the Pharmacokinetic Profile of Propylene Glycol (PG) in Healthy Adults Following PG Exposure

Brief Summary: The goal of this clinical trial is to determine the translation of propylene glycol (PG) exposure in beverages to circulating PG levels to better understand the margin of safety in healthy participants. The main question it aims to answer is what is the maximum concentration (Cmax) of propylene glycol (PG) in serum following consumption of one, two, or three PG-containing beverages? Participants will be asked to:* Consume 1x, 2x, and 3x 12oz of PG-containing beverage* Have their blood drawn* Complete urine…

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