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Course: Pseudorheumatoid Nodules of the Eyelid in a Boy Aged 4 Years

CME Credits: 1.00

Released: 2022-07-21

A 4-year-old boy with no medical history presented with a lesion over the left eyelid, which had grown progressively in size over a 4-month period (). There were no changes in vision, nor did the boy report pain. A review of systems was negative, and basic bloodwork was normal. An excisional biopsy was performed. Histopathology revealed epithelioid histiocytes palisading around degenerated collagen. A diagnosis of pseudorheumatoid nodule was made. Pseudorheumatoid nodules are rare lesions around the orbit (more typically seen on the legs, scalp, or feet) and are typically well demarcated, small, and painless. They are histologically similar to rheumatoid nodules but found in patients without evidence of any concurrent systemic illness.- These lesions often spontaneously regress over time; biopsy is needed to confirm diagnosis. Treatment includes observation or surgical excision. The authors note the importance of a systemic evaluation to rule out concurrent disease. Importantly, patients are not believed to be at increased risk of future development of autoimmune disease.,


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