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Course: Retinopathy in Presumed Congenital Rubella Syndrome

CME Credits: 1.00

Released: 2022-07-21

A 56-year-old woman was referred by an optometrist for evaluation of retinal degeneration. She was asymptomatic in both eyes, and her vision was 20/25 OU. Anterior segment examination was unremarkable. Her past medical history was significant for deafness, patent ductus arteriosus, pulmonary stenosis, maternal rubella infection during gestation (no antibody testing results were available), and short stature. Optos ultra-widefield retinal imaging showed widespread retinal pigment epithelial changes in both eyes (). Lesions involved the majority of the posterior pole, and areas of most severe degeneration were seen near the optic nerve head and large vessels surrounding the macula. Fluorescein angiography demonstrated staining of the retinal pigment epithelial changes and a large window defect in the superior aspect of the left macula (). This is a case of presumed extensive congenital rubella syndrome with no visual sequelae identified. Deafness, cardiac defects, and pigmentary retinopathy are among the most frequent manifestations of congenital rubella syndrome.-


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