Course: Optic Nerve–Associated Astrocytic Hamartoma With Corresponding Visual Field Defect
CME Credits: 1.00
Released: 2022-03-17
A 66-year-old Black man presented for routine eye examination. Best-corrected visual acuity was 20/20 OU. Dilated fundus examination demonstrated a solitary multilobulated lesion located superonasally over the right optic nerve head (, A). Examination of the fellow eye was unremarkable. A 24-2 Humphrey visual field test (Zeiss) revealed a corresponding inferotemporal defect (, A inset). The patient had no medical or family history of seizures or dermatologic abnormalities suggestive of tuberous sclerosis complex. On swept-source optical coherence tomography, the raised lesion had an irregular surface and multifocal internal lucencies (, B) consistent with a calcified retinal astrocytic hamartoma with optic nerve involvement., Other conditions considered included optic nerve head drusen and acquired retinal astrocytoma. Although commonly asymptomatic when isolated, these lesions may cause visual field defects depending on their anatomic location or degree of optic nerve involvement. The lesion was observed, and all findings (including the visual field defect) remained stable through 10 years of follow-up.
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