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Research Article: The therapeutic effect of IPL on children with vernal keratoconjunctivitis

Date Published: 2026-06-22

Abstract:
To observe the effectiveness of intense pulsed light (IPL) treatment as an adjuvant treatment of vernal keratoconjunctivitis (VKC) in children. Sixty-two children diagnosed with VKC from January 2022 to November 2024 were selected and divided into the IPL group (27 cases, conventional drug therapy combined with IPL treatment) and the control group (35 cases, conventional drug therapy). Symptom and sign indicators were tested before treatment (baseline) and after the end of treatment. The Treatment course, recurrence time and the number of adverse reactions for each group of patients were recorded. There was no statistically significant difference in the treatment course between the two groups ( P > 0.05); IPL treatment independently and significantly extended the recurrence interval in children with VKC (log-rank P = 0.003). There were no adverse reaction in either group during the treatment. IPL can effectively prolong the recurrence interval of VKC, and has good safety.

Introduction:
Vernal keratoconjunctivitis (VKC) ( 1 ) is a chronic ocular inflammatory disease with a tendency for seasonal recurrence, involving the cornea and conjunctiva. It commonly occurs in children and adolescents, especially those under the age of ten. The main symptoms and signs include eye itching, foreign body sensation, increased secretions, conjunctival congestion, edema, palpebral conjunctival papillae hyperplasia, and Horner-Trantas nodules at the corneal limbus. The pathogenesis of VKC may involve genetics,…

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