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Research Article: Summary of the best evidence for non-pharmacological management of dysphagia in Parkinson’s disease patients

Date Published: 2026-06-15

Abstract:
This study systematically synthesizes the best available evidence for the non-pharmacological management of swallowing disorders in Parkinson’s disease, establishing an actionable framework to standardize clinical implementation and optimize multidisciplinary care pathways. Based on the “6S” evidence resource model, a systematic search was conducted for all evidence on dysphagia management in Parkinson’s disease, including guidelines, expert consensuses, clinical decision-making tools, and systematic reviews. The search period spanned from the inception of the database up to December 31, 2024. Three researchers independently screened and evaluated the literature, and subsequently, two researchers extracted and summarized the evidence in accordance with the JBI grading of evidence and recommendation system. A total of 18 pieces of literature were included, encompassing 2 guidelines, 4 expert consensuses, 11 systematic reviews, and 1 clinical decision-making document. The evidence covered 7 categories, with a total of 53 best evidence items identified, including screening, assessment, rehabilitation, nutritional management, airway and complication management, and outcome evaluation. This study comprehensively and scientifically summarizes the best evidence for the non-pharmacological management of swallowing disorders in patients with Parkinson’s disease. Users of this evidence should consider specific clinical contexts during the translation of evidence and select appropriate evidence-based interventions to develop individualized and localized management plans.

Introduction:
Parkinson’s disease (PD), also known as paralysis agitans, is the second most common neurodegenerative disease following Alzheimer’s ( 1 ). It is primarily characterized by clinical motor symptoms such as resting tremor, bradykinesia, unstable gait, and muscle rigidity, as well as non-motor symptoms including autonomic nervous system dysfunction, sleep disorders, cognitive impairment, and abnormal mental behaviors ( 1 ). Approximately 36.9 to 80% of PD patients experience dysphagia ( 2–4 ). Among them, about 10.87…

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