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Research Article: Impact of multi-channel follow-up as continuous nursing on cancer pain control, adverse reactions, and quality of life in patients with digestive tract tumors: a controlled study of 136 cases

Date Published: 2026-07-20

Abstract:
This study was designed to assess the effectiveness of multi-channel follow-up as a continuous nursing intervention in monitoring pain relief, adverse effects and quality of life in patients with digestive tract tumors following their discharge. A total of 136 patients were recruited from the Department of Medical Oncology and Department of Tumor Radiotherapy from July 2023 to July 2025 in this prospective controlled study. Participants were averagely and randomly assigned into the experimental group (n=68) that received multi-channel follow-up (including nurse-led telephone assessments, WeChat platform-based monitoring, and home visits) and a control group (n=68) that received standard telephone follow-up. Pain intensity and patient-reported satisfaction with pain control were primary outcomes. Secondary outcome measures included constipation, other analgesic-related adverse events, and quality of life. The experimental group had statistically significant lower pain scores and higher pain control satisfaction compared with the control group. The incidence of constipation was also lower in the experimental group, while no remarkable difference was found in other analgesics-related adverse drug reactions (ADRs). The quality of life was significantly improved in the experimental group as the increased number of cases with good sleep quality (PSQI ?7) was observed in the experimental group when compared to the control group. The association between pain intensity and sleep disturbance appeared to weaken after accounting for group assignment. Multi-channel follow-up as continuity-of-care nursing improved pain control, reduced constipation, and enhanced sleep quality among post-discharge patients with digestive tract tumors. The observed association between pain intensity and sleep quality was attenuated after adjustment for group assignment and should be interpreted as associative rather than causal.

Introduction:
Pain remains a common and clinically significant symptom in patients with digestive tract tumors and might be related to physical activity, emotional distress, and general quality of life (QoL) impairment ( 1 ). A recent systematic review and meta-analysis reported that the overall prevalence of pain among patients with cancer was 44.5%, and moderate-to-severe pain was present in 30.6% of patients, indicating that cancer pain remains a major supportive-care issue despite improvements in assessment and management (…

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