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Association of the TyG index and inflammatory burden index with AMR-defined coronary microvascular dysfunction and 12-month MACE after STEMI

Abstract: Metabolic dysfunction and inflammation may jointly contribute to coronary microvascular injury and adverse outcomes after primary percutaneous coronary intervention…

Date: 2026-08-07

Rapid on–off effects of methotrexate on lymphocytes may facilitate recovery of suppressed vaccine immunogenicity after its short-term methotrexate discontinuation in rheumatoid arthritis

Abstract: Short-term methotrexate (MTX) discontinuation restores vaccine responses in rheumatoid arthritis (RA). We investigated how the timing of MTX exposure relative to…

Date: 2026-08-07

Development of an HDL-C combined with AJCC staging system for predicting overall survival after curative resection of intrahepatic cholangiocarcinoma without metabolic comorbidities

Abstract: To develop and validate a prognostic model integrating HDL-C and AJCC staging system for predicting overall survival (OS) in patients with intrahepatic…

Date: 2026-08-07

Perception of family relationships and depressive symptoms in older adults in Loja, Ecuador: an analytical cross-sectional study

Abstract: Family relationships are an important psychosocial determinant of mental health in older adults. Their perception of family functioning may differ from that of other…

Date: 2026-08-07

Adjunctive Chaihu Guizhi Tang combined with Maxing Shigan Tang and short-term clinical recovery in hospitalized older adults with community-acquired pneumonia: a prospective non-randomized controlled study

Abstract: Older adults hospitalized with community-acquired pneumonia (CAP) often recover slowly despite standard care. Chaihu Guizhi Tang combined with Maxing Shigan Tang (CHGZ +…

Date: 2026-08-07

Clinical and genetic evidence from East Asian cohorts linking family history burden and menarche timing to curve severity in adolescent idiopathic scoliosis

Abstract: Adolescent idiopathic scoliosis (AIS) affects 2% to 3% of adolescents and progresses rapidly during puberty. Previous studies suggest that a positive family history of…

Date: 2026-08-07

Tobacco use patterns and the social environment among university students in southern Ecuador

Abstract: Tobacco use remains a public health concern, particularly among young people, due to their greater vulnerability to smoking initiation and maintenance, as well as the…

Date: 2026-08-07

Analysis of risk factors for severe acute poisoning in children

Abstract: To identify independent risk factors for the progression of acute poisoning to severe cases in children, and to provide a basis for early clinical identification and…

Date: 2026-08-07

Postpartum glucose follow-up after gestational diabetes in China: provider and institutional determinants in a multicenter survey across urban public hospitals

Abstract: Postpartum glucose follow-up after gestational diabetes mellitus (GDM) represents an important opportunity for early diabetes risk identification and long-term type 2…

Date: 2026-08-07

Study on the expression of p53, PTEN, and p16 in endometrial polyps of breast cancer patients receiving endocrine therapy: a comparative study of immunohistochemistry

Abstract: This study aims to compare the expression of p53, PTEN, and p16 among three groups: endometrial polyps of breast cancer patients receiving endocrine therapy, common…

Date: 2026-08-07