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Unanticipated discovery: basal metabolic rate as an independent risk factor for metabolic dysfunction-associated steatotic liver disease in a 5-year longitudinal cohort study of non-obese individuals in China

Abstract: The role of basal metabolic rate (BMR) in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) remains controversial, with previous studies yielding…

Date: 2025-09-01

Application of machine learning for prognostic modeling in unresectable pancreatic cancer treated with chemoradiotherapy

Abstract: Patients with unresectable pancreatic cancer have poor outcomes despite chemoradiotherapy (CRT). Traditional prognostic tools lack accuracy in predicting survival. This…

Date: 2025-09-01

Association of low serum 25-hydroxyvitamin D levels with hearing loss severity in Meniere disease: a cross-sectional study

Abstract: Growing evidence implicates vitamin D in inner ear homeostasis, though its association with Ménière’s disease (MD) remains incompletely characterized. This study aimed…

Date: 2025-09-01

Real-world data on adult AML with FLT3 -ITD mutation from the Thai acute leukemia working group

Abstract: FLT3 -ITD mutations are among the most common genetic alterations in acute myeloid leukemia (AML) and are associated with poor clinical outcomes. However, data from low-…

Date: 2025-08-29

Standard dose and low-dose rituximab combined with glucocorticoids and cyclophosphamide in the treatment of acquired haemophilia A

Abstract: To investigate the efficacy and safety of standard dose and low-dose rituximab combined with corticosteroids and cyclophosphamide in the treatment of acquired…

Date: 2025-08-29

Management of intermediate high-risk pulmonary embolism: a single-center retrospective study

Abstract: Approximately 25% of PE cases are intermediate-risk, with mortality rates between 5% and 25%. Management strategies for intermediate-risk PE remain inconsistent. This…

Date: 2025-08-29

ISI matsuda as a potential predictor of metabolic dysfunction-associated steatotic liver disease in patients with type 2 diabetes mellitus

Abstract: This study aimed to determine the most efficacious insulin resistance (IR) indices to predict metabolic dysfunction-associated steatotic liver disease (MASLD) in…

Date: 2025-08-29

Exercise training improves metabolic and circulatory function in COPD patients with NAFLD: evidence from clinical and molecular profiling

Abstract: Non-alcoholic fatty liver disease (NAFLD) and chronic obstructive pulmonary disease (COPD) are frequently comorbid, affecting up to 41% of COPD patients. Both conditions…

Date: 2025-08-29

Differential expression and correlation analysis of whole transcriptome for type 2 diabetes mellitus

Abstract: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that accounts for 90% or more of all diabetes cases and contributes to the global public health burden.…

Date: 2025-08-29

The association between obstructive sleep apnoea and diabetic peripheral neuropathy in subjects with type 2 diabetes

Abstract: This study aimed to examine the association between obstructive sleep apnoea (OSA) and diabetic peripheral neuropathy (DPN) in subjects with type 2 diabetes mellitus…

Date: 2025-08-29