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Neuroimaging characteristics associated with early neurological deterioration in single subcortical infarction patients

Abstract: Single subcortical infarctions (SSIs) are frequently complicated by early neurological deterioration (END), which adversely impacts long-term functional outcomes.…

Date: 2026-08-05

Longitudinal trajectories of neurologic symptoms and cognitive associations at 36-months post-hospitalization for COVID-19

Abstract: A substantial proportion of individuals hospitalized for COVID 19 experience persistent neurological and psychiatric symptoms. The long-term trajectories of these…

Date: 2026-08-05

Neuromodulatory effects of N-acetyl-L-leucine in a human induced neuronal cell culture system

Abstract: N-acetyl-L-leucine (NALL), an acetylated derivative of the amino acid leucine, has been shown to reduce neuronal cell death and neuroinflammation in murine models. Its…

Date: 2026-08-05

Lacunar stroke with and without chronic imaging biomarkers of small vessel disease: clinical profiles and stroke etiology

Abstract: Chronic cerebral small vessel disease (CSVD) may help distinguish different etiological mechanisms in acute lacunar stroke; this study aimed to compare vascular risk…

Date: 2026-08-05

Interferon-?-induced tolerogenic dendritic cells ameliorate autoimmune neuroinflammation and suppress T-cell responses in multiple sclerosis

Abstract: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system characterized by immune-mediated demyelination and neuroinflammation resulting from…

Date: 2026-08-05

Serum metabolomics modelling reveals stage-associated purine and endocannabinoid metabolic signatures in colorectal cancer progression

Abstract: Colorectal cancer (CRC) remains one of the major challenges in contemporary oncology. Despite advances in imaging diagnostics and histopathological assessment, we still…

Date: 2026-08-05

Dual optimization in single-isocenter radiosurgery for multiple brain metastases: a dosimetric planning study

Abstract: This study evaluated a dual-optimization strategy for single-isocenter multiple-target stereotactic radiosurgery (SIMT-SRS) in patients with multiple brain metastases,…

Date: 2026-08-05

The role of the preoperative HALP score in predicting pathological T and N categories in colon cancer: a single-center retrospective study

Abstract: The HALP score is an easily accessible immunonutritional biomarker that may reflect systemic inflammation and nutritional status. This study aimed to evaluate the…

Date: 2026-08-05

The combined compartmental maxillary resection: technique codification and preliminary multicenter series analysis

Abstract: Maxillary cancers extending to the deep craniofacial spaces represent one of the most challenging scenarios in head and neck oncology. Integrating compartmental surgery…

Date: 2026-08-05

Perioperative outcomes and prognostic determinants in adult spindle cell/sclerosing rhabdomyosarcoma: implications of treatment intensity, surgical margins, and molecular heterogeneity

Abstract: Spindle cell/sclerosing rhabdomyosarcoma (ssRMS) represents an uncommon and biologically heterogeneous soft tissue sarcoma with clinical outcomes in adults markedly…

Date: 2026-08-05