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Epidemiological analysis of Lambert-Eaton myasthenic syndrome in Türkiye: insights from a nationwide electronic health database

Abstract: Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disorder of the neuromuscular junction, with limited large-scale epidemiological data. In this study, we…

Date: 2025-08-25

Engrafted NSG-SGM3 humanized mice spontaneously produce human immunoglobulins including IgE

Abstract: NSG-SGM3 humanized mouse models are well-suited for studying human immune physiology but are technically challenging and expensive. We previously characterized a…

Date: 2025-08-25

Insights into genetic and clinical profiles of triple A syndrome in Sudanese children

Abstract: Triple A syndrome (OMIM*231550) is a rare autosomal recessive disorder characterized by achalasia, alacrima, adrenal insufficiency, and neurological features. It is…

Date: 2025-08-22

Pustular reaction in adult-onset immunodeficiency due to anti-interferon-gamma autoantibodies

Abstract: Cutaneous manifestations in adult-onset immunodeficiency (AOID) resulting from anti-interferon-gamma autoantibody (AIGA) are prevalent and can be classified into…

Date: 2025-08-22

Determinants of vaccination coverage during the COVID-19 pandemic among children aged 12–23 months in southern Ethiopia: a cross-sectional study

Abstract: Millions of children, particularly in low and middle-income countries, are deprived of a comprehensive vaccination schedule. The advent of the COVID-19 pandemic…

Date: 2025-08-22

Assessing TDApp: An AI-based clinical decision support system for ADHD treatment recommendations

Abstract: Clinical practice guidelines (CPGs) have several limitations, namely: obsolescence, lack of personalization, and insufficient patient participation. These factors may…

Date: 2025-08-22

Impact of gonadotropin genetic profile and ovarian reserve on controlled ovarian stimulation: data from prospective cohort of the GENOCS trial

Abstract: Several studies indicate that a specific genotype profile could influence ovarian sensitivity to exogenous gonadotropin. However, most of the previous studies were…

Date: 2025-08-22

HIV risk perception and associated factors among pregnant and breastfeeding women in Zambia: implications for PrEP uptake in antenatal and postnatal settings

Abstract: HIV risk perception is seen as a key motivation for individuals to use biomedical HIV prevention interventions, including pre-exposure prophylaxis (PrEP). We determined…

Date: 2025-08-22

Cognitive functions among Saudi patients with methamphetamine and cannabis use disorder

Abstract: Methamphetamine use disorder (MUD) is linked to a variety of cognitive and neuropsychiatric deficits. One of the illegal substances that is most frequently abused is…

Date: 2025-08-22

The non-linear association of physical fatigue with depression and anxiety among mental health professionals who recovered from COVID-19 infection: a national survey in China

Abstract: The COVID-19 pandemic took a toll on everyone’s health and mental health professionals were no exception. This study examined the trajectory of the relationship between…

Date: 2025-08-22