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Novel proteomics biomarkers of recurrent pregnancy loss reflect the dysregulation of immune interactions at the maternal-fetal interface

Abstract: Miscarriages affect 50-70% of all gestations and 15-20% of clinically recognized pregnancies. Recurrent pregnancy loss (RPL) occurs in 1-5% of clinical pregnancies and…

Date: 2025-08-28

Preliminary insights into cardiopulmonary reserve and hemodynamic stability: exploring submaximal cardiopulmonary exercise testing parameters as potential predictors of intraoperative hemodynamic instability

Abstract: Intraoperative hypotension (IOH) is associated with serious adverse outcomes after noncardiac surgery. Preoperative predictors of IOH remain poorly characterized.…

Date: 2025-08-28

Pharmacist-assisted implementation of guideline recommendations for QTc monitoring during psychopharmacotherapy - a prospective, randomized feasibility study

Abstract: Many psychotropic drugs potentially prolong the QTc interval. The aim of this study was to investigate the feasibility of the pharmacist-supported implementation of a…

Date: 2025-08-28

Accumulated lifetime violence load and interpersonal problems among suicidal women with emotionally unstable personality disorder

Abstract: Patients with emotionally unstable personality disorder (EUPD) report increased use and exposure to interpersonal violence and experience significant interpersonal…

Date: 2025-08-28

Digital loneliness as a new diagnostic category in psychiatry: the impact of technology and social media use on psychological well-being

Abstract: The aim of this study was to determine the impact of social media use on users’ subjective feelings of loneliness and the occurrence of anxiety symptoms, taking into…

Date: 2025-08-28

Prevalence and correlates of depression and depression-anxiety in patients receiving gastroscopy

Abstract: There are increasing numbers of patients suffering from gastrointestinal disorders who are at primary risk for depression. These patients often have no awareness of…

Date: 2025-08-28

Application of mirror reconstruction and 3D printing technology in the treatment of Sanders type IV calcaneal fractures

Abstract: To explore the clinical efficacy of an integrated workflow combining mirror reconstruction and 3D printing for Sanders type IV calcaneal fractures—a severely comminuted…

Date: 2025-08-28

The burden of surgical site infection and associated factors among patients admitted to the surgical ward in resource-limited countries: an institutional-based cross-sectional study

Abstract: Surgical site infections (SSIs) are a leading cause of morbidity and mortality worldwide. Particularly, in low- and middle-income countries (LMICs), they are the most…

Date: 2025-08-28

Effect of electroencephalogram-guided anesthesia on postoperative delirium in older adults after surgery: a systematic review and meta-analysis

Abstract: Postoperative delirium is a frequent and severe complication among elderly surgical patients. Electroencephalogram (EEG)-guided anesthesia, which optimizes sedation…

Date: 2025-08-28

The global burden of childhood diarrhea and its epidemiological characteristics from 1990 to 2021

Abstract: Diarrhea diseases remains a major contributor to global mortality and morbidity in children. This study aims to provide an updated assessment of rates in diarrhoea…

Date: 2025-08-28