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Value of a BRAF V600E and lymphocyte subset-based nomogram for discriminating benign lesions from papillary thyroid carcinoma in C-TIRADS 3 and higher nodules

Abstract: The BRAF V600E mutation and lymphocyte subsets may be associated with papillary thyroid carcinoma (PTC). This study established and validated a nomogram model to…

Date: 2025-08-15

Expression levels of T cell-related immune factors and their correlation with thyroid function in Graves’ disease with varied serum iodine status: insights into immunopathogenesis

Abstract: Measurement of Serum Iodine Concentration (SIC) in Newly Diagnosed Adult Graves’ Disease (GD) Patients with Hyperthyroidism and Healthy Controls: Investigating Cytokine…

Date: 2025-08-15

Development of a transtheoretical model for the prevention and treatment of skin disease through ultraviolet protection based on 14,681 samples of outpatient clinics and a cross-sectional survey

Abstract: Little is known about the association between types of skin and subcutaneous diseases and UV protection literacy. To assess the burden and treatment of skin diseases in…

Date: 2025-08-15

The influence of hypertensive disorders in pregnancy on neonatal amino acid and acylcarnitine levels

Abstract: Hypertensive disorders in pregnancy (HDP) are associated with an increased risk of neonatal complications; however, their effects on neonatal metabolism remain…

Date: 2025-08-15

An exploratory single-cell analysis of peripheral blood mononuclear cells from vedolizumab-treated Crohn’s disease patients identifies response-associated differences among the plasmacytoid dendritic cells and classical monocytes

Abstract: Vedolizumab (VDZ) is a monoclonal antibody approved for the treatment of Crohn’s disease (CD). Despite its efficacy, non-response to VDZ is common in clinical practice…

Date: 2025-08-15

Lipoprotein combine index is associated with non-alcoholic fatty liver disease: a 5-year longitudinal cohort study in non-obese Chinese populations with normal lipids

Abstract: Current evidence concerning the association between lipoprotein combine index (LCI) and Non-alcoholic fatty liver disease (NAFLD) in non-obese people remains limited.…

Date: 2025-08-15

Pre-infusion ferritin a predictive biomarker for CAR T-cell therapy in R/R multiple myeloma

Abstract: Evaluating predictive biomarkers early in treatment, clinicians can anticipate Q7 77 78 survival outcomes. Ferritin has emerged as a promising predictor of clinical 79…

Date: 2025-08-14

Impact of the COVID-19 pandemic on the Andalusian program for early detection of diabetic retinopathy: a population-based study

Abstract: To analyze the impact of the COVID-19 pandemic on the activity and outcomes of the Andalusian Program for Early Detection of Diabetic Retinopathy (APDR). A retrospective…

Date: 2025-08-14

Correlation analysis of thyroid function and vitamin D levels in patients with type 2 diabetes

Abstract: This study investigated the association between vitamin D status and thyroid function in 1,805 adults with type 2 diabetes mellitus (T2DM) treated at a tertiary hospital…

Date: 2025-08-14

A microscopic transungual surgical approach for subungual glomus tumor resection

Abstract: Glomus tumors, rare benign neoplasms developing from the glomus, often pose challenges in early detection due to their small size and subtle symptoms. Surgical removal…

Date: 2025-08-14