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Correlation between TyG index and its modified index with breast cancer risk in women a study based on NHANES database and real-world data

Abstract: To evaluate the association between the triglyceride-glucose (TyG) index and its modified indices with the risk of female breast cancer using data from the National…

Date: 2026-07-21

Prognostic analysis of first-recurrence/metastasis esophageal squamous cell carcinoma: chemoimmunotherapy combined with radiotherapy as one of the optimal clinical management strategies

Abstract: The real-world efficacy and prognostic factors of First-line and subsequent-line treatment for first-recurrent/metastatic esophageal squamous cell cancer (ESCC) have not…

Date: 2026-07-21

A modified stent-free Chen's U-suture technique in pediatric pancreaticojejunostomy: safety and efficacy

Abstract: Pediatric pancreatic surgery is challenging due to soft pancreatic texture and small main pancreatic duct (MPD) diameter, both risk factors for postoperative pancreatic…

Date: 2026-07-21

Long-term SGLT2 inhibitor therapy improves myocardial strain and diastolic function in HFpEF: a retrospective study linking functional recovery to reduced myocardial fibrosis

Abstract: The pathophysiological mechanisms of heart failure with preserved ejection fraction (HFpEF) are complex, with myocardial fibrosis being one of its core features, closely…

Date: 2026-07-21

Clinical outcomes of Impella 5+ in acute myocardial infarction-related cardiogenic shock: a retrospective single-center study

Abstract: Temporary mechanical circulatory support (t-MCS) with Impella CP has recently attracted considerable interest as a therapeutic option for cardiogenic shock (CS)…

Date: 2026-07-21

CAR-T versus allogeneic transplantation as consolidation for B-cell acute lymphoblastic leukemia in remission: a propensity-score matched study

Abstract: Despite being a standard consolidation treatment, allogeneic hematopoietic stem cell transplantation (allo-HSCT) for B-cell acute lymphoblastic leukemia (B-ALL) in…

Date: 2026-07-20

Outcomes and predictors of second haploidentical hematopoietic stem cell transplantation for pediatric acute leukemia relapsing after a first allograft

Abstract: The clinical efficacy and prognostic factors of haploidentical hematopoietic stem cell transplantation (haplo-HSCT) as a salvage approach for children with relapsed…

Date: 2026-07-20

Explainable machine learning for osteoporosis detection in patients with osteopenia: model development and validation using routine clinical data from an Asian cohort

Abstract: Osteopenia is a critical precursor to osteoporosis (OP), yet accurately discriminating OP from osteopenia among individuals with low bone mass remains challenging. While…

Date: 2026-07-20

Micromegaly: a distinct clinical entity? Insights from a monocentric cohort study

Abstract: The term “micromegaly” historically refers to patients with acromegalic features, elevated IGF-1, but normal growth hormone (GH) levels. The physiological mechanism, the…

Date: 2026-07-20

IgE levels correlate with Fc ? RI expression on circulatory basophils but not with their activation response in patients with Hymenoptera anaphylaxis

Abstract: Measurement of IgE levels, skin prick tests (SPT), and basophil activation tests (BAT) are the gold standards for diagnosing Hymenoptera allergy. Currently, BAT most…

Date: 2026-07-20