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A nomogram integrating machine learning with clinical predictors for osteosarcopenia risk prediction in type 2 diabetes mellitus

Abstract: Type 2 diabetes mellitus (T2DM) predisposes patients to osteosarcopenia, a debilitating condition characterized by concurrent bone loss and muscle wasting. This study…

Date: 2026-07-15

Association between albuminuria and prevalent diabetic retinopathy in type 2 diabetes: a cross-sectional study with exploratory analysis by carotid plaque status

Abstract: Diabetic retinopathy (DR) and diabetic kidney disease share common microvascular mechanisms, whereas carotid plaque reflects systemic atherosclerotic burden in type 2…

Date: 2026-07-15

Nutrient metabolic heterogeneity across renal stages in patients with type 2 diabetes mellitus and diabetic kidney disease

Abstract: Diabetic kidney disease (DKD) is a nutrition-related complication of type 2 diabetes mellitus (T2DM) characterized by complex disturbances in glucose, lipid, purine, and…

Date: 2026-07-15

Proteomics and transcriptomics reveal molecular subtypes and biomarkers of advanced cutaneous T-cell lymphoma

Abstract: Cutaneous T-cell lymphomas (CTCL) are a group of non-Hodgkin T-cell lymphomas, with mycosis fungoides and Sézary syndrome being the most common subtypes. Advanced-stage…

Date: 2026-07-15

Influencing factors of peripheral blood indicators on 30-day mortality risk in children with hemophagocytic lymphohistiocytosis based on weighted quantile sum regression: a single-center retrospective cohort study

Abstract: To investigate the joint effect of peripheral blood parameters on the 30-day mortality risk in children with hemophagocytic lymphohistiocytosis (HLH) using weighted…

Date: 2026-07-15

Real-world patterns of inflammatory bowel disease treatment across adult and pediatric populations: a nationwide cohort study in South Korea

Abstract: Although understanding real-world treatment patterns for inflammatory bowel disease (IBD) from initial diagnosis across age groups is essential, most studies focus on…

Date: 2026-07-15

Admission-time immunologic patterns in hospitalized children with Mycoplasma pneumoniae pneumonia: a molecular load–antibody titer phenotyping analysis

Abstract: Targeted next-generation sequencing (tNGS) provides a semi-quantitative signal of Mycoplasma pneumoniae (MP) molecular burden, whereas antibody titers reflect humoral…

Date: 2026-07-15

Chemokine-receptor-dependent inflammatory responses contribute to two-hit-induced experimental necrotizing enterocolitis and represent a potential therapeutic target

Abstract: Necrotizing enterocolitis (NEC) is a severe multifactorial inflammatory disorder of the preterm intestine for which effective preventive and therapeutic strategies…

Date: 2026-07-15

dNLR, NLR, and NMLR as differential markers for assessing severity and sepsis in emphysematous pyelonephritis

Abstract: This study aims to evaluate the association between blood count-derived inflammatory markers and the severity of radiographic disease, as well as the presence of sepsis…

Date: 2026-07-15

Persistent racial and socioeconomic inequities in mycosis fungoides survival: a population-based study

Abstract: Racial disparities in mycosis fungoides (MF) have been described historically, but their persistence in the contemporary era of diagnosis and care remains incompletely…

Date: 2026-07-15