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Assessment of treatment effectiveness, follow-up results, and recurrence patterns in children with Helicobacter pylori infection

Abstract: Helicobacter pylori infection remains a prevalent chronic bacterial condition in children and is associated with significant long-term gastrointestinal complications,…

Date: 2026-04-23

Reticular dysgenesis caused by AK2 deficiency: clinical spectrum and hematopoietic stem cell transplantation outcomes in 10 patients from a single-center

Abstract: Reticular dysgenesis (RD), caused by biallelic variants in AK2 , represents the most severe and rare form of Severe Combined Immunodeficiency, characterized by profound…

Date: 2026-04-23

The influence of family care guidance for premature infants based on a telemedicine model on their neurodevelopmental assessment indicators

Abstract: Premature infants, defined as those born before 37 weeks of gestation, are at elevated risk for neurodevelopmental delay due to incomplete organ maturation and…

Date: 2026-04-23

Circadian disruption associated with nighttime light exposure contributes to airway epithelial remodeling via TIMELESS in childhood asthma

Abstract: Childhood asthma is a common inflammatory airway disease, and its occurrence is influenced by environmental factors. Artificial light at night (ALAN) can disrupt…

Date: 2026-04-23

Cross-ancestry analysis of gestational diabetes mellitus identifies novel loci, drug targets and biological pathways

Abstract: Gestational diabetes mellitus (GDM) is a common pregnancy complication with adverse maternal and fetal outcomes, yet its genetic basis is not fully understood. Previous…

Date: 2026-04-23

Epidemiological investigation of fetal laterality disorders in multiple hospitals in coastal Southeastern China before and after the COVID-19 pandemic (2017–2024)

Abstract: Fetal laterality disorders are rare congenital anomalies including situs inversus, partial heterotaxy, and heterotaxy syndrome. They are associated with increased risks…

Date: 2026-04-23

Association between nursing execution and postoperative recovery following laparoscopic benign gynecologic surgery: a prospective observational cohort study

Abstract: Enhanced Recovery After Surgery (ERAS)-based perioperative care is widely implemented in gynecologic laparoscopy, yet the real-world execution of nursing practices…

Date: 2026-04-23

S-ketamine mitigates paclitaxel-induced pain-related anxiety-like behavior through downregulation of mGluR5 and activation of the BDNF/TrkB signaling pathway

Abstract: Paclitaxel (PTX), a broad-spectrum anti-tumor drug, is extensively employed as a first-line chemotherapy for solid tumors, including lung and breast cancers. However, it…

Date: 2026-04-23

Development of a preoperative risk score for predicting blood transfusion in pediatric scoliosis surgery: a two-center retrospective cohort study

Abstract: Despite recent advancements in blood conservation strategies, perioperative allogeneic red blood cell (RBC) transfusion remains common in pediatric patients undergoing…

Date: 2026-04-23

Perioperative anesthetic management in patients undergoing resection of giant abdominal masses: a retrospective analysis of 21 cases

Abstract: To summarize perioperative anesthetic management in patients undergoing resection of giant abdominal masses. Perioperative data from 21 patients who underwent resection…

Date: 2026-04-23