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Machine learning prediction of adverse events during minutes 15–30 of recovery in patients event-free at 15?min after sedated gastrointestinal endoscopy

Abstract: Sedated gastrointestinal (GI) endoscopy is widely used for diagnosis and treatment but may be complicated by respiratory and hemodynamic adverse events (AEs) during…

Date: 2026-08-27

A high-risk sepsis subtype identified by regulated cell death signatures and MAD2L2 validation

Abstract: Regulated cell death (RCD) is closely involved in immune dysregulation and organ injury during sepsis, yet the coordinated transcriptional features of multiple RCD…

Date: 2026-08-27

Day-4 antipseudomonal and anti-MRSA de-escalation was not associated with higher mortality in critically ill patients with sepsis

Abstract: Broad empiric antibiotics are often appropriate at the start of intensive care unit (ICU) sepsis care; however, continued antipseudomonal or anti-methicillin-resistant…

Date: 2026-08-27

Chelidonic acid ameliorates Aspergillus fumigatus keratitis via antifungal and anti-inflammatory activities

Abstract: This study aimed to evaluate the therapeutic efficacy of chelidonic acid (CA) in Aspergillus fumigatus ( AF )-induced keratitis and to elucidate the underlying molecular…

Date: 2026-08-27

Aggregate index of systemic inflammation and glaucoma status: population-based evidence with clinical validation

Abstract: Glaucoma is a major cause of irreversible visual impairment, but evidence on the association between the aggregate index of systemic inflammation (AISI) and glaucoma…

Date: 2026-08-27

Impact of COVID-19 on corneal endothelial density and morphology: a cross-sectional study in convalescent patients

Abstract: This study aimed to investigate the effect of COVID-19 infection on corneal endothelial cell density and morphology, and to analyze the related factors. This…

Date: 2026-08-27

Transcriptome-based profiling of programmed cell death signatures identifies two osteoarthritis subtypes and the hub gene DNM1L

Abstract: Osteoarthritis (OA) poses a significant global health risk, with programmed cell death (PCD) playing a key role in its development. This study utilized integrated…

Date: 2026-08-27

Association of preoperative fasting blood glucose with 1-year Harris Hip Score after hip fracture in older adults: a multicenter retrospective cohort study

Abstract: The impact of preoperative fasting blood glucose (FBG) on functional recovery after hip fracture remains uncertain. We conducted a multicenter retrospective cohort study…

Date: 2026-08-27

High prevalence of fatigue in patients with inflammatory bowel disease: association with physical activity intensity and sedentary behavior

Abstract: Fatigue is reported to be a common and disabling manifestation in patients with inflammatory bowel disease. Specialized units and nurse-led services play key roles in…

Date: 2026-08-27

Integrated multi-omics identification of m6A-SNP-related diagnostic biomarkers in amyotrophic lateral sclerosis

Abstract: Amyotrophic lateral sclerosis (ALS) lacks reliable and minimally invasive biomarkers for early diagnosis. m6A-associated single-nucleotide polymorphisms (m6A-SNPs) may…

Date: 2026-08-27