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Serum copeptin predicts atrial fibrillation recurrence and is associated with increased all-cause mortality

Abstract: Copeptin, a stable surrogate marker of arginine vasopressin, reflects neurohumoral activation and hemodynamic stress. Its prognostic value in heart failure is…

Date: 2026-08-25

Enhanced sialylation of bone marrow mesenchymal stromal cells contributes to immune remodeling through macrophage polarization in multiple myeloma patients

Abstract: In multiple myeloma (MM), the immune system is disrupted, partly due to tumor-modified bone marrow mesenchymal stromal cells (BM-MSCs). These MSCs show altered…

Date: 2026-08-25

Polish translation and validation of the student satisfaction and self-confidence in learning scale among healthcare students at the Pomeranian Medical University in Szczecin: a single-center cross-sectional validation study

Abstract: Simulation-based education is an established component of healthcare training, yet robust Polish-language instruments for evaluating the learner’s reaction to simulation…

Date: 2026-08-25

Hypertension identified in early adulthood as an endocrine–vascular risk factor for uterine fibroids in reproductive-age women: a nationwide cohort study

Abstract: The association between hypertension identified in early adulthood and uterine fibroid development in young women remains poorly understood. Therefore, we aimed to…

Date: 2026-08-25

Cardiac and systemic biological age capture complementary aging signals associated with cardiovascular disease

Abstract: Biological ages capture aging signatures associated with aging-related outcomes, but most models use systemic and unimodal indices. The added value of organ-specific and…

Date: 2026-08-25

Low-dose allergen targeting to cDC2 induces long-term protection associated with induction of regulatory-like IL-10 + Foxp3 - CD8 + T cells in mice

Abstract: The prevalence of allergic diseases is rising worldwide. Desensitizing immunotherapy is currently the only available treatment, but it is often ineffective for certain…

Date: 2026-08-25

Neutrophil extracellular trap-associated responses are associated with tissue factor expression and coagulation abnormalities during anaphylaxis

Abstract: Anaphylaxis is a severe, fast-onset hypersensitivity reaction. Studies have shown that neutrophils play an important role in the acute phase of anaphylaxis. Activated…

Date: 2026-08-25

Developing a prediction model of neonatal pneumonia in patients with gestational diabetes mellitus in primary medical institutions

Abstract: The incidence of gestational diabetes mellitus (GDM) continues to rise in China, and the risk of neonatal pneumonia is significantly increased, but the primary medical…

Date: 2026-08-25

A decade-long assessment reveals persistent vitamin D deficiency and its associated factors in early-pregnant women from northern China (2016–2025)

Abstract: Large-scale data on vitamin D status in early-pregnant women in high-risk Northern China are scarce. This study evaluated the decadal trends (2016–2025) and associated…

Date: 2026-08-25

Suggestive genome-wide associations with inflammatory biomarkers in an admixed population, including a missense variant in the OR6K6 olfactory receptor gene associated with MCP-1

Abstract: Chronic low-grade inflammation drives cardiometabolic diseases and has a strong genetic basis. Most genome-wide association studies (GWAS) have focused on European…

Date: 2026-08-25