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Bispecific nanobodies targeting Bet v 1 and ICAM-1 decrease respiratory epithelial penetration of Bet v 1

Abstract: The major birch pollen allergen Bet v 1 primarily affects the nose and eyes of allergic patients. After crossing the epithelial barrier, it causes IgE-mediated effector…

Date: 2026-08-17

Analysis of cross-provincial healthcare utilization among hospitalized patients in a tertiary Chinese medicine hospital

Abstract: To analyze the current situation and changing trends of cross-provincial healthcare utilization among hospitalized patients in a tertiary Chinese medicine hospital,…

Date: 2026-08-17

Explainable multimodal fusion model integrating clinical and quantitative CT features for preoperative prediction of high-grade histologic patterns in invasive lung adenocarcinoma

Abstract: Accurate preoperative prediction of high-grade patterns in invasive lung adenocarcinoma is critical for effective treatment planning. This study aimed to construct an…

Date: 2026-08-17

Deep learning model for differentiating acute and chronic osteoporotic vertebral compressive fractures on multidetector CT: a retrospective study with external validation

Abstract: Osteoporotic vertebral compression fractures (OVCFs) are a common spinal disease. Differentiating acute and chronic fractures is the key to determining the treatment…

Date: 2026-08-17

Diagnostic value of whole-tumor ADC histogram parameters combined with ISUP grade and MRI-EPE score for predicting extracapsular extension in PI-RADS 4–5 prostate cancer

Abstract: To investigate the incremental value of whole-tumor apparent diffusion coefficient (ADC) histogram parameters, when combined with clinical pathological variables for…

Date: 2026-08-17

Construction and practice of a multi-station Chinese medicine specialist nurse training system based on core competencies: a Delphi study

Abstract: With the increasing global recognition of traditional Chinese medicine (TCM), the standardized training of TCM specialist nurses remains challenging due to the lack of…

Date: 2026-08-17

Real-world evidence on migraine treatment in routine clinical practice: insights from the Türkiye migraine registry study using artificial intelligence algorithms

Abstract: Despite available diagnostic and therapeutic options, a major unmet need persists in migraine care. This study applied artificial intelligence (AI) to extract structured…

Date: 2026-08-17

Factors associated with history of suicide attempt among patients with major depressive disorder at a community mental health center in the Peruvian Andes: a case-control study

Abstract: A history of suicide attempt among patients with major depressive disorder has been associated with clinical, psychosocial, and familial vulnerabilities, yet evidence…

Date: 2026-08-17

Elevated serum IL-18 and IL-37 levels and their association with seizure burden in paediatric epilepsy

Abstract: Neuroinflammation is increasingly recognized as a key contributor to epileptogenesis and epilepsy progression. Interleukin-18 (IL-18), a pro-inflammatory cytokine of the…

Date: 2026-08-17

Social media use motives and academic performance among Saudi medical students: the mediating role of perceived stress

Abstract: A growing body of research has documented associations between social media use and perceived stress. However, the psychological mechanisms underlying these…

Date: 2026-08-17