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Assessment of brachial plexus and upper-extremity peripheral nerve injuries at the anatomical level using multimodal generative models

Abstract: Injuries to the brachial plexus and its terminal branches can be devastating at the functional and occupational levels, as loss of even partial functions causes major…

Date: 2026-08-13

Feasibility and clinical efficacy of minimally invasive techniques in the treatment of type ?/? brucellar spondylitis

Abstract: To explore the clinical feasibility and perioperative superiority of combined minimally invasive techniques in treating type II/III Brucellar Spondylitis (BS), clarify…

Date: 2026-08-13

Circulating microRNAs as biomarkers of disease activity and treatment response in Crohn’s disease patients receiving infliximab or vedolizumab: a longitudinal cohort study

Abstract: Validated biomarkers of biologic response in Crohn’s disease (CD) are lacking. We assessed whether serum microRNAs (miRNAs) track disease activity and predict outcomes…

Date: 2026-08-13

Resveratrol alleviates functional dyspepsia-like pathology by modulating chemokine- and cytokine-related immune–epithelial signaling in the duodenal mucosa

Abstract: Resveratrol is a dietary polyphenol found in grapes, peanuts, and berries, with reported anti-inflammatory, immunomodulatory, barrier-protective, and…

Date: 2026-08-13

Single-cell and spatial landscape reveals impaired tertiary lymphoid structure maturation in Helicobacter pylori –associated gastric cancer

Abstract: Tertiary lymphoid structures (TLSs) are key immune niches involved in antitumor immunity. However, their functional impact depends on spatial localization, maturation…

Date: 2026-08-13

Expanding the clinical spectrum of CD3? deficiency: comprehensive characterization of adult-onset disease and integrated reevaluation of all reported patients

Abstract: CD3? deficiency is an ultrarare autosomal recessive inborn error of immunity characterized by immune dysregulation and variable immunodeficiency. To date, only 16…

Date: 2026-08-13

Human beta defensins 3 and 6 serve as diagnostic tools for identifying sepsis and pneumonia

Abstract: Sepsis poses significant challenges in early detection and treatment due to its heterogeneous nature and overlaps with other conditions, such as pneumonia. Identifying…

Date: 2026-08-13

Spatial and temporal immune landscapes of non-necrotic granulomas in two murine tuberculosis models with divergent disease outcomes

Abstract: Tuberculosis (TB), caused by Mycobacterium tuberculosis , continues to be a major health issue worldwide. Granulomas are characteristic lesions of TB, functioning both…

Date: 2026-08-13

Disease-specific biomarker value of C-reactive protein and its composite indices in autoinflammatory diseases: an integrated study of multi-modal omics and population cohorts

Abstract: Autoinflammatory diseases (AIDs) are a heterogeneous group of innate immune-driven disorders whose prevalence is rising globally, yet the lack of disease-specific…

Date: 2026-08-13

Interpretable machine learning prognostication of gastroenteropancreatic neuroendocrine tumors across Chinese and United States cohorts

Abstract: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) display marked clinical heterogeneity, and conventional prognostic indicators such as TNM stage and Ki-67 index…

Date: 2026-08-13