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Exploring the relationship between uric acid-to-HDL cholesterol ratio and vascular calcification: evidence from clinical, genetic, and network-based analyses

Abstract: Vascular calcification (VC) is a multifactorial process associated with adverse cardiovascular outcomes. The uric acid to high-density lipoprotein cholesterol ratio…

Date: 2026-08-12

Factors associated with psychiatric admission from observation beds in the psychiatric emergency room

Abstract: Psychiatric emergency services frequently utilize observation units to support disposition decisions when diagnostic uncertainty exists, allowing for extended…

Date: 2026-08-12

Aggressive and self-harming behaviour among psychiatric inpatients in a specialised prison hospital: a retrospective cohort study

Abstract: Aggressive behaviour and self-harming behaviour are common psychiatric emergencies in correctional settings, yet little is known about the factors distinguishing these…

Date: 2026-08-12

Artificial intelligence-integrated multimodal retinal imaging for early detection and risk stratification of systemic vascular and neurodegenerative diseases

Abstract: We developed and validated RetinalVNG-Net, a multimodal deep learning framework for simultaneous risk stratification of hypertensive retinopathy, diabetic retinopathy,…

Date: 2026-08-12

Loss of Akt3 enhances antiviral immunity while disrupting corneal homeostasis during ocular HSV-1 infection

Abstract: Akt1 and Akt2 isoforms reveal distinct immune-regulatory roles in HSV-1 pathogenesis. Akt3 is a developmentally important protein, and mutations in Akt3 gene are…

Date: 2026-08-12

Differential efficacy of Conbercept vs. Ranibizumab on retinal microstructural changes in macular edema secondary to retinal vein occlusion during the loading phase

Abstract: To compare the efficacy of Conbercept vs.Ranibizumab on retinal microstructural changes in patients with retinal vein occlusion-associated macular edema (RVO-ME) by…

Date: 2026-08-12

Evaluation of a large language model for clinician-facing preoperative cost-communication preparation in total knee arthroplasty

Abstract: Costs associated with total knee arthroplasty (TKA) may affect treatment preparation, expectation management, and postoperative care planning. Previous large language…

Date: 2026-08-12

Comparison of two postoperative complication grading systems following an elective orthopedic procedure in dogs

Abstract: A standardized system for grading postoperative complications in veterinary orthopedics was proposed in 2010 by Cook et al. categorizing complications as minor, major,…

Date: 2026-08-12

Unveiling Fusobacterium nucleatum ’s role in colorectal cancer: the inflammatory microenvironment connection

Abstract: Fusobacterium nucleatum (Fn), a gram-negative oral bacterium, has been implicated in promoting colorectal cancer (CRC) progression by modulating the inflammatory…

Date: 2026-08-12

Reflux esophagitis patients exhibit reduced gastric tolerance, impaired slow-wave activity and esophageal dysmotility

Abstract: Reflux esophagitis (RE) is an endoscopic subtype of gastroesophageal reflux disease (GERD). Although gastric dysfunction is known to contribute to GERD, a comprehensive…

Date: 2026-08-12