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BCG overexpressing Ag85B reprograms host immune response through coordinated transcriptional networks

Abstract: Antigen 85B (Ag85B), an immunodominant protein secreted by Mycobacterium tuberculosis (Mtb), induces robust T-cell-mediated immunity in host cells. Previous studies have…

Date: 2026-08-12

DLL3 expression in neuroendocrine carcinomas: a comparative analysis across tumor origins

Abstract: Neuroendocrine carcinomas (NECs) are rare and highly aggressive tumors, characterized by a dismal prognosis. Their underlying biology remains insufficiently understood,…

Date: 2026-08-12

The prognostic value of triglyceride glucose–waist height ratio index in patients with heart failure after acute myocardial infarction: a retrospective study

Abstract: Heart failure (HF) after acute myocardial infarction (AMI) remains a major clinical challenge. The triglyceride glucose-waist-to-height ratio (TyG-WHtR) integrates…

Date: 2026-08-12

Prognostic value of the systemic immune-inflammation index in acute limb ischemia undergoing endovascular therapy

Abstract: Acute limb ischemia (ALI) is a vascular emergency associated with major amputation and mortality, highlighting the need for early risk stratification. The systemic…

Date: 2026-08-12

Intensive vs. standard nurse-supervised blood pressure monitoring and intensive care utilization in acute hypertensive encephalopathy: a single-center retrospective cohort study

Abstract: Acute hypertensive encephalopathy (AHE), a subtype of posterior reversible encephalopathy syndrome (PRES), requires rapid blood pressure control and intensive…

Date: 2026-08-12

The ApoB/ApoA-I ratio and the risk of in-stent restenosis following drug-eluting stent implantation in patients with coronary heart disease: a retrospective cohort study

Abstract: The Apolipoprotein B/Apolipoprotein A-I (ApoB/ApoA-I) ratio has been strongly associated with the risk of cardiovascular disease. However, its association with in-stent…

Date: 2026-08-12

Circulating excitation–contraction coupling proteins and incident cardiovascular outcomes: associations and incremental predictive performance in the UK Biobank

Abstract: Excitation–contraction coupling is central to cardiovascular physiology, but the prospective relevance of circulating proteins involved in this pathway remains…

Date: 2026-08-12

Plasma miR-148b-3p is associated with CKD-related renal dysfunction and carotid plaque burden in patients with established coronary artery disease

Abstract: Chronic kidney disease (CKD) is associated with increased atherosclerotic burden and vascular risk, particularly in patients with established coronary artery disease…

Date: 2026-08-12

Long-term effects of permanent pacemaker therapy on growth in children with complete heart block

Abstract: Complete heart block (CHB) is a rare but potentially life-threatening condition in childhood. A permanent pacemaker (PM) can provide a physiologically appropriate heart…

Date: 2026-08-12

Nonlinear association between body fat percent and type 2 diabetes risk in Japanese adults: a retrospective cohort study

Abstract: Type 2 diabetes (T2D) has emerged as a major global public health challenge, with dyslipidemia playing a pivotal role in its pathogenesis. Body fat percentage (BFP), a…

Date: 2026-08-11