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Explainable machine learning for 2-year functional outcomes in older adults with aneurysmal subarachnoid hemorrhage in North China: external validation and health-system context

Abstract: Older adults with aneurysmal subarachnoid hemorrhage (aSAH) have heterogeneous long-term outcomes, and differences in treatment pathways and hospital capacity may…

Date: 2026-09-25

Exploration of miRNAs promoting eosinophilia and type 2 immunity

Abstract: MicroRNAs (miRNAs) are evolutionary conserved, small non-coding RNAs that regulate gene expression and modulate cellular responses. In this study, we profiled miRNAs…

Date: 2026-09-25

Real-world clinical outcomes and safety of anlotinib-containing regimens in pediatric solid tumors: a retrospective cohort study at a Chinese center

Abstract: This retrospective cohort study aimed to characterize the real-world clinical outcomes and treatment-emergent adverse events (TEAEs) of anlotinib-containing regimens…

Date: 2026-09-25

Development and external validation of a nomogram to predict survival and guide surgical strategy for colorectal cancer with synchronous liver and lung metastases: a SEER-based analysis

Abstract: Surgical management of colorectal cancer with synchronous liver and lung metastases (CRC-SLLM) remains challenging because of marked clinical heterogeneity, and reliable…

Date: 2026-09-25

Distinct circular RNA signatures distinguish STEMI from NSTEMI in acute myocardial infarction

Abstract: Heart attacks come in different forms, with ST-elevation myocardial infarction (STEMI) and non-ST-elevation myocardial infarction (NSTEMI) being two important but…

Date: 2026-09-25

The development of nomograms to predict multiple pregnancy and multiple birth in frozen- thawed embryo transfer cycles: a retrospective study

Abstract: This study aimed to identify key factors influencing multiple pregnancy (MP) and multiple birth (MB) rates in frozen- thawed embryo transfer (FET) cycles, and to develop…

Date: 2026-09-25

Teaching and assessment strategies in the obstetrics and gynaecology program: medical students' perceptions evaluation

Abstract: Worldwide, medical institutions face challenges in maintaining educational quality while accommodating the growing size of student cohorts. Assessment and critical…

Date: 2026-09-25

Triglyceride–glucose index and preserved ratio impaired spirometry in 89,809 individuals without self-reported overt clinical disease

Abstract: While both preserved ratio impaired spirometry (PRISm) and triglyceride glucose index (TyG) are established risk factors for cardiometabolic diseases, the metabolic…

Date: 2026-09-25

Maternal emotional distress, caregiving burden, and service access among mothers of children with autism spectrum disorder: a qualitative study

Abstract: Mothers raising children with autism spectrum disorder (ASD) may experience substantial emotional distress and caregiving burden, whilst family support andaccess to…

Date: 2026-09-25

Predictors of postpartum coparenting relationship among primiparous couples in Karachi, Pakistan

Abstract: The postpartum coparenting relationship is an important determinant of parental well-being, relationship functioning, and child development during the transition to…

Date: 2026-09-25