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SULT1A1 at a differentiation branch point regulates osteosarcoma cell proliferation and melatonin-mediated anti-tumor activity

Abstract: Circadian disruption is increasingly recognized as a contributing factor in tumorigenesis and tumor evolution; however, the role of circadian genes in osteosarcoma cell…

Date: 2026-07-07

Integrative analysis of GEO data on the microbial community in colorectal cancer tissues and its impact on the tumor immune microenvironment

Abstract: Colorectal cancer (CRC) development is closely associated with gut microbiota dysbiosis and disruption of the tumor immune microenvironment. This study aimed to…

Date: 2026-07-07

Factors associated with type 1 gastric neuroendocrine tumor occurrence in autoimmune atrophic gastritis: insights from a real-world cohort

Abstract: Autoimmune gastritis (AIG) is characterized by chronic inflammation and represents a key step in the multistage precancerous process of the stomach. Patients with AIG…

Date: 2026-07-07

ATF3 and HNF4A: an oxidative phosphorylation and cholesterol homeostasis-associated diagnostic and therapeutic repurposing framework target for metabolic dysfunction-associated steatohepatitis patients

Abstract: Metabolic dysfunction-associated steatohepatitis (MASH) is hepatic steatosis. Oxidative phosphorylation and cholesterol homeostasis (OC) plays a key role in the onset…

Date: 2026-07-07

Association between the C-reactive protein–triglyceride–glucose index and coronary heart disease in metabolic dysfunction-associated steatotic liver disease patients: a cross-sectional study

Abstract: Metabolic dysfunction-associated steatotic liver disease (MASLD) is strongly associated with coronary heart disease (CHD), but convenient and effective biomarkers for…

Date: 2026-07-07

Dietary index for gut microbiota and risk of incident gastroesophageal reflux disease: a prospective cohort analysis integrating plasma proteomics in the UK Biobank

Abstract: Gastroesophageal reflux disease (GERD) is a common chronic digestive disorder, and diet is an important modifiable risk factor. The Dietary Index for Gut Microbiota…

Date: 2026-07-07

Construction and validation of a nomogram for predicting pathological upgrading/progression of gastric low-grade intraepithelial neoplasia

Abstract: To analyze the clinical, endoscopic, and pathological characteristics of gastric low-grade intraepithelial neoplasia (LGIN), identify independent risk factors for…

Date: 2026-07-07

Clinical implications of free triiodothyronine levels and diagnostic revisions in antibody-negative autoimmune encephalitis

Abstract: Low triiodothyronine (T3) syndrome has been associated with initial clinical severity and poor long-term functional outcomes in autoimmune encephalitis (AE). However,…

Date: 2026-07-07

Combined nutritional and inflammatory risk stratification for predicting functional outcomes in acute ischemic stroke

Abstract: Inflammation and malnutrition are both closely associated with adverse outcomes after acute ischemic stroke (AIS), yet their combined effect and potential interaction…

Date: 2026-07-07

Cerebral artery stump syndrome: a comprehensive pooled analysis of 188 angiographically confirmed cases

Abstract: Cerebral artery stump syndrome (CASS), a rare aetiology of ischemic stroke, consists of two subtypes: carotid stump syndrome (CSS) and vertebral artery stump syndrome…

Date: 2026-07-07