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Rituximab in Myasthenia Gravis: a real-world study using inverse probability of treatment weighting

Abstract: The role of rituximab in the treatment of myasthenia gravis (MG) remains uncertain due to limited randomized controlled evidence and heterogeneous observational data.…

Date: 2026-07-02

Immunological coagulation dual axis stratification identifies ultra high-risk phenotypes in systemic sclerosis

Abstract: Systemic sclerosis is a heterogeneous autoimmune disease characterized by complex interplay among immune activation, inflammation, coagulation, and fibrinolysis. This…

Date: 2026-07-02

Aquaporin-5–specific heavy chain VDJ knock-in (A5H) mice reveal molecular mimicry–driven initiation and diversification of autoreactive B-cell responses

Abstract: Molecular mimicry, where microbial antigens resemble self-antigens, is implicated in triggering autoimmune responses, yet the early B-cell events leading to autoantibody…

Date: 2026-07-02

Longitudinal changes in oral conditions and oral candidiasis in palliative care inpatients: a longitudinal observational study

Abstract: Oral health influences comfort, communication, and quality of life in palliative care. However, its clinical drivers and prognostic significance remain poorly…

Date: 2026-07-02

Repurposing tricyclic drugs as cancer therapeutics: comparative analysis of antitumorigenic effects of chlorpromazine, amitriptyline and imipramine

Abstract: Tricyclic drugs such as chlorpromazine (CPZ), amitriptyline (AmiT), and imipramine (ImiP) have demonstrated antitumorigenic potential, yet their relative potency and…

Date: 2026-07-02

Application of unilateral biportal endoscopy in minimally invasive treatment of non-aggressive spinal benign tumors: technical note and preliminary clinical study

Abstract: To introduce the technical protocol of unilateral biportal endoscopy (UBE) in the treatment of patients with non-aggressive spinal benign tumors and evaluate its…

Date: 2026-07-02

Crucial role of IL-6, IL-8, IL-11 and leptin in tumor microenvironment in a group of patients with GEP-NETs- crosstalk between inflammation and cancer

Abstract: GEP-NETs constitute a heterogeneous group of rare cancers arising in biologically diverse microenvironments, while their cytokine profiles remain insufficiently…

Date: 2026-07-02

Insulin resistance as a predictor of long-term adverse cardiovascular event risk in patients with atrial fibrillation following radiofrequency catheter ablation

Abstract: Catheter ablation is the first-line therapy for atrial fibrillation (AF), yet a significant proportion of patients experience major adverse cardiovascular events (MACEs)…

Date: 2026-07-02

Association of the combined triglyceride glucose-body mass index and serum IQGAP3 in appraising coronary lesion severity in type 2 diabetes

Abstract: IQGAP3 is a novel scaffold protein involved in inflammatory and metabolic regulation and may contribute to atherosclerosis. However, its clinical significance in…

Date: 2026-07-02

Freely accessible large language models for parent education in pediatric immune thrombocytopenia: an expert-rated cross-sectional study of safety, readability, and guideline concordance

Abstract: Parents of children with immune thrombocytopenia (ITP) increasingly turn to freely available large language models (LLMs) when they need quick explanations. In pediatric…

Date: 2026-07-01