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Duodenal dysbiosis is linked to altered ferroportin related transcriptomics programs in iron deficiency anemia

Abstract: Iron deficiency anemia (IDA) affects over two billion people, yet up to half of patients show inadequate response to oral iron therapy. We hypothesized that IDA is a…

Date: 2026-07-01

Impact of reperfusion on thrombectomy outcomes in patients with pre-stroke disability

Abstract: Mechanical thrombectomy (MT) is frequently performed beyond traditional eligibility criteria, yet the clinical benefits for patients with pre-stroke disability remain…

Date: 2026-07-01

Dynamic changes and associated factors of asymmetric prominent vessel sign in atherosclerotic anterior circulation acute ischemic stroke: a preliminary study

Abstract: To investigate the dynamic changes, influencing factors, and prognostic significance of the asymmetric prominent vessel sign (APVS) in patients with atherosclerotic…

Date: 2026-07-01

Burden level and influencing factors of caregivers for patients with autoimmune encephalitis

Abstract: Caregiver burden is a critical issue in neurological disorders, but remains underexplored in autoimmune encephalitis (AE), a severe condition on patients and their…

Date: 2026-07-01

Regional disparities and hospital performance patterns in acute stroke reperfusion: a multicenter study in Sichuan Province, China

Abstract: Timely reperfusion is critical to improving outcomes in acute ischemic stroke (AIS). However, disparities in treatment quality and accessibility persist across hospital…

Date: 2026-07-01

Cognitive impairment in Chinese patients with isolated generalized dystonia: a case–control study

Abstract: Previous studies have indicated that non-motor symptoms are primary problems in focal dystonia, but limited data are available about cognitive function and their…

Date: 2026-07-01

TLR7 signaling aggravates lung inflammation associated with increased anti-Scl-70 autoantibody production in murine bleomycin-induced systemic sclerosis

Abstract: Systemic sclerosis (SSc) is a severe autoimmune disease characterized by immune dysregulation, fibrosis, and substantial morbidity and mortality. Although type I…

Date: 2026-07-01

Immune profiling shows limited systemic changes in children with autism after autologous cord blood transfusion

Abstract: Autism spectrum disorder (ASD or autism) is a neurodevelopmental condition characterized by social difficulties and restricted, repetitive behaviors, and is a leading…

Date: 2026-07-01

Differential generation of parasite-specific Th2 and T follicular helper cells distinguishes resistant and susceptible mouse strains

Abstract: Both T helper 2 (Th2) and B cell responses are crucial for controlling gastrointestinal (GI) nematode infections. However, adaptive immune determinants of host…

Date: 2026-07-01

LAG3-centered multiplex immune profiling as a prognostic biomarker in hepatocellular carcinoma patients receiving Anti-PD-1 antibodies plus lenvatinib therapy

Abstract: This study aims to investigate the characteristics and functional status of the lymphocyte-activation gene-3 (LAG-3), cluster of differentiation 8 (CD8), programmed cell…

Date: 2026-07-01