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Reliability and reproducibility of the modified thoracolumbar injury classification and severity score and the thoracolumbar AO spine injury score for guiding surgical decision-making in thoracolumbar fractures

Abstract: To evaluate the reliability and reproducibility of the modified Thoracolumbar Injury Classification and Severity Score (mTLICS) and the Thoracolumbar AO Spine Injury…

Date: 2026-06-26

An innovative 2D optical navigation workflow for percutaneous pedicle screw fixation in thoracolumbar fractures: comparison with O-arm 3D navigation

Abstract: Thoracolumbar fractures (TLFs) are common spinal injuries caused by high-energy trauma, falls, or osteoporosis. Traditional open surgery may involve substantial blood…

Date: 2026-06-26

Knowledge gaps, psychological burden, and patient-reported symptom severity and daily functioning in autoimmune gastritis: a observational survey of Chinese patients

Abstract: Autoimmune Gastritis (AIG) is a chronic inflammatory disorder characterized by autoimmune-mediated damage to the gastric mucosa, leading to gastric atrophy and may…

Date: 2026-06-26

Dietary diversity, migration experience, and brain volume in middle-aged and older adults in rural Japan: a cross-sectional magnetic resonance imaging study

Abstract: To identify lifestyle, social, and health-related factors associated with normalized brain volume (NBV), an imaging marker of brain atrophy, among community-dwelling…

Date: 2026-06-26

HMGB1-TLR4 signaling-mediated neuroinflammation contributes to the pathogenesis of infantile epileptic spasms syndrome in rats

Abstract: Infantile epileptic spasm syndrome (IESS) is a severe age-dependent epileptic encephalopathy in infancy with poor prognosis and unclear pathogenesis. Neuroinflammation…

Date: 2026-06-26

Patient and caregiver perspectives on transition from pediatric to adult care in inborn errors of immunity: a Polish multicenter survey

Abstract: Advances in the diagnosis and treatment of inborn errors of immunity (IEI) have improved survival rates, resulting in a growing population of adolescents requiring…

Date: 2026-06-26

The associations between nailfold microvascular abnormalities and systemic inflammation or Th17/Treg dysregulation in rheumatoid arthritis

Abstract: To investigate the abnormal characteristics of nailfold microcirculation (NMC) in patients with rheumatoid arthritis (RA) and to further analyze the associations between…

Date: 2026-06-26

Immune-dominated cellular heterogeneity and stromal plasticity in keloid infiltrating and hypercellular zones revealed by single-cell RNA sequencing

Abstract: Keloids are aggressive fibroproliferative disorders characterized by a sclerotic core and an actively invading margin, yet the cellular and molecular basis of this…

Date: 2026-06-26

Assessing the multi-software robustness of radiomic biomarkers: a three-tool evaluation

Abstract: To assess the cross-software reproducibility of Computed Tomography (CT) radiomic features extracted using three widely adopted platforms (Siemens syngo.via Frontier, 3D…

Date: 2026-06-26

Navigating specific targets of psychoneurological symptom cluster in breast cancer: a computer-simulated network analysis

Abstract: Sleep disturbance, cancer-related fatigue, emotional distress (anxiety and depression), and pain, collectively known as psychoneurological symptom cluster (PNSC), were…

Date: 2026-06-26