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Association between H. pylori infection status, UBT-derived DOB level, and colorectal polyp detection

Abstract: To investigate the associations of Helicobacter pylori ( H. pylori ) infection status and urea breath test-derived delta over baseline (DOB) values with colorectal polyp…

Date: 2026-06-09

Diagnostic performance of three-dimensional high-resolution anorectal manometry in identifying descending perineal syndrome

Abstract: Three-dimensional high-resolution anorectal manometry (3DHRAM) has been developed and introduced to explore pelvic floor disorder. The aim of this study was to evaluate…

Date: 2026-06-09

Antibodies against Ro52 in idiopathic inflammatory myopathies are associated with objective sicca symptoms

Abstract: Autoantibodies against Ro52 are not only detected in Sjögren’s disease (SjD), but also in idiopathic inflammatory myopathies, where they correlate with the incidence and…

Date: 2026-06-09

Adverse pregnancy outcome associations among women prior to a diagnosis of systemic lupus erythematosus

Abstract: Immune dysregulation years prior to a clinical diagnosis of systemic lupus erythematosus (SLE) may include a range of asymptomatic autoantibody positivity to clinically…

Date: 2026-06-09

Noncanonical NF-?B pathway driven inflammation across multiple cellular compartments identifies NIK as a therapeutic target for inflammatory bowel disease

Abstract: The noncanonical NF-?B pathway, driven by NF-?B-inducing kinase (NIK), plays a central role in inflammatory bowel disease (IBD) pathogenesis by regulating immune…

Date: 2026-06-09

Implications of systolic pulmonary artery pressure trajectories in systemic lupus erythematosus-associated pulmonary hypertension: a CSTAR-PAH cohort study

Abstract: To identify the evolution trajectory of systolic pulmonary artery pressure (sPAP) in patients with systemic lupus erythematosus-related pulmonary arterial hypertension…

Date: 2026-06-09

Angiosarcoma in a soft tissue sarcoma cohort: real-world patterns and outcomes

Abstract: Angiosarcoma is a rare, aggressive vascular sarcoma with heterogeneous clinical presentation and limited real-world outcome data. We retrospectively reviewed adult soft…

Date: 2026-06-09

RSPO2-induced ferroptosis via PTBP1-mediated FSP1 mRNA decay suppresses breast cancer progression

Abstract: Breast cancer is the most common malignant tumor worldwide, and its high heterogeneity limits the efficacy of current clinical therapies. R-spondin 2 (RSPO2) expression…

Date: 2026-06-09

Subcutaneous patient-controlled analgesia with hydromorphone for the treatment of refractory cancer pain in older hospitalized patients: a retrospective real-world study

Abstract: Refractory cancer pain remains difficult to control in older adults, particularly when oral opioid regimens are limited by dysphagia, nausea, bowel dysfunction, or…

Date: 2026-06-09

SIMVASTATIN as a potential protective strategy against doxorubicin-induced cardiotoxicity

Abstract: Doxorubicin-induced cardiotoxicity (DIC) represents a major limitation in oncology, leading to ventricular dysfunction and long-term morbidity. Lipophilic statins, such…

Date: 2026-06-09