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Differences in clinical features and prognosis between hypertriglyceridemia and other causes of acute pancreatitis: a dual perspective based on metabolic disorders and inflammatory response

Abstract: To investigate the clinical features and prognosis of acute pancreatitis (AP) with different etiologies. A total of 242 patients with AP admitted to the First Affiliated…

Date: 2026-06-10

Urinary fatty acid binding protein 2 as a biomarker of intestinal injury in pediatric celiac disease

Abstract: Celiac disease (CeD) is an autoimmune enteropathy triggered by gluten in genetically predisposed individuals, causing intestinal damage and impaired gut barrier…

Date: 2026-06-10

PolyMamba-Net: a lightweight and boundary-aware network for real-time polyp segmentation in colonoscopy

Abstract: Colorectal cancer (CRC) is a leading cause of cancer-related mortality globally. The early detection and resection of adenomatous polyps via colonoscopy are critical for…

Date: 2026-06-10

Machine learning-based prediction of gout flares during hospitalization in patients with upper gastrointestinal bleeding: a retrospective cohort study

Abstract: Acute gout flares pose a significant therapeutic challenge in hospitalized patients with upper gastrointestinal bleeding (UGIB) due to the contraindications of standard…

Date: 2026-06-10

Clinical and genetic characteristics of children with sodium taurocholate cotransporting poly-peptide deficiency

Abstract: Sodium taurocholate cotransporting polypeptide deficiency (NTCPD) is an autosomal recessive disorder caused by SLC10A1 gene mutations. This study analyzed the clinical…

Date: 2026-06-10

ANGPT1–GABARAP axis modulates NLRP3 inflammasome–mediated pyroptosis in Crohn’s disease

Abstract: Crohn ’ s disease (CD) is characterized by persistent intestinal inflammation, immune dysregulation, and intestinal barrier dysfunction. Inflammasome-mediated pyroptosis…

Date: 2026-06-10

Development and validation of a machine learning model for predicting stroke-associated pneumonia in older patients with acute ischemic stroke

Abstract: Stroke-associated pneumonia (SAP) is a common and serious complication in older patients with acute ischemic stroke (AIS). However, early identification of high-risk…

Date: 2026-06-10

Soluble multi?epitope protein vaccination leverages antigen availability to drive CD8 + T cell immunity and tumor control

Abstract: The shift toward precision medicine in cancer immunotherapy has increased demand for rapid, scalable production platforms for personalized vaccine antigens targeting…

Date: 2026-06-10

Association between the C-reactive protein–triglyceride–glucose index and incident cardiovascular disease in middle-aged and older adults with arthritis: a nationwide prospective cohort study with hospital-based cross-sectional replication

Abstract: Arthritis encompasses heterogeneous joint and rheumatic conditions and is associated with increased cardiovascular disease (CVD) risk. The C-reactive…

Date: 2026-06-10

Influencing factors and path analysis of posttraumatic growth in patients with autoimmune diseases

Abstract: Guided by the Transactional Model of Stress and Coping, this study aimed to construct a structural equation model of posttraumatic growth in patients with autoimmune…

Date: 2026-06-10