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Retrospective evaluation of the prevalence of known and presumed hereditary eye diseases in a population of Labradoodles referred for ophthalmic screening examinations in the Netherlands

Abstract: The popularity of designer crossbreed dogs, including Labradoodles, has increased markedly in recent years. This retrospective study evaluated ophthalmic findings and…

Date: 2026-06-08

Digital eye strain among Indian university students in the post-COVID era: a cross-sectional study

Abstract: Digital Eye Strain (DES), also known as Computer Vision Syndrome (CVS), has become increasingly prevalent with the expansion of digital device use, particularly in…

Date: 2026-06-08

Widefield SS-OCTA-detected retinal vascular changes and their correlation with DME in diabetes

Abstract: This study investigated retinal blood flow alterations in diabetic macular edema (DME) using ultra-widefield optical coherence tomography angiography (OCTA). We enrolled…

Date: 2026-06-08

V-shaped capsular plication for treating cam-type femoroacetabular impingement with hip instability in borderline dysplastic hips: a retrospective cohort study

Abstract: Purpose Patients with cam-type femoroacetabular impingement (FAI) frequently present with concomitant borderline developmental dysplasia of the hip (BDDH), a critical…

Date: 2026-06-08

Laminectomy vs. laminoplasty for treating multi-segment cervical canal stenosis combined with central cord syndrome in the absence of fracture or dislocation: a retrospective study

Abstract: Laminectomy fusion fixation (LF) and single open-door laminoplasty (LP) are common posterior surgeries for central cord syndrome without fracture/dislocation (CCSWOFD),…

Date: 2026-06-08

Development and internal validation of a prediction model for hypoxic hepatitis after coronary artery bypass grafting with cardiopulmonary bypass

Abstract: Hypoxic hepatitis (HH) after on-pump coronary artery bypass grafting (CABG) is associated with poor outcomes, but dedicated prediction tools are lacking. We developed…

Date: 2026-06-08

TPPU protects against seizures and seizure-associated comorbidities by inhibiting the Akt/mTOR signaling pathway in KA-induced convulsant mice

Abstract: Shared pathophysiological mechanisms exist between epilepsy and its associated comorbidities, with neuroinflammation playing a key role.…

Date: 2026-06-08

First-line serplulimab plus chemotherapy versus chemotherapy alone in small-cell lung cancer patients with brain metastases: a multicenter, prospective cohort study

Abstract: Immunochemotherapy is standard for small-cell lung cancer (SCLC), yet efficacy and safety of serplulimab for patients with brain metastases (BM) remain to be fully…

Date: 2026-06-08

Antitumoral efficacy of silver nanoparticles reduced with ?-D-glucose on a canine transmissible venereal tumor cell line

Abstract: Canine transmissible venereal tumor represents a significant threat to animal health, particularly due to the large global population of stray dogs. The standard…

Date: 2026-06-08

An exploratory integrative analysis of plasma transcriptomic and proteomic predictors of response to total neoadjuvant therapy in locally advanced rectal cancer

Abstract: LARC patients exhibit heterogeneity in their response to total neoadjuvant therapy (TNT). This study aims to screen and identify plasma biomarkers associated with…

Date: 2026-06-08