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Optimization of nursing strategies for semaglutide treatment in overweight type 2 diabetes based on gene polymorphism

Abstract: To evaluate the impact of a gene polymorphism-based individualized nursing strategy on the efficacy of semaglutide in overweight type 2 diabetes (T2DM) patients and to…

Date: 2026-05-18

Association between Staphylococcus aureus colonization and clinical improvement in pediatric atopic dermatitis treated with dupilumab: a pilot study

Abstract: Moderate-to-severe atopic dermatitis (AD) in children is characterized by impaired skin barrier function, type 2 inflammation, and frequent Staphylococcus aureus…

Date: 2026-05-18

Microcrystalline tyrosine as a novel depot-forming agent in venom immunotherapy: a pre-clinical evaluation in bee-venom allergic mice

Abstract: Venom immunotherapy (VIT) with aqueous venom extracts is a standard treatment for severe insect venom allergies. In other fields of allergen immunotherapy (AIT), depot…

Date: 2026-05-18

A prediction nomogram for faltering catch-up growth in full-term small-for-gestational-age infants: a retrospective cohort study

Abstract: Catch-up growth (CUG) before two years of age in small-for-gestational-age (SGA) infants is a key predictor of adult short stature. We aimed to establish and temporally…

Date: 2026-05-18

Aberrant IL-21/STAT3 signaling disrupts regulatory T cell function and CD4 + T cell homeostasis in children with type 1 diabetes

Abstract: Type 1 diabetes (T1D) is an autoimmune disease characterized by profound dysregulation of CD4 + T cell subsets, particularly impaired regulatory T cell (Treg) function…

Date: 2026-05-18

Comparison of the therapeutic performance of macrolide antibiotics on macrolide-resistant or macrolide-susceptible Mycoplasma pneumoniae pneumonia children

Abstract: This research aims to investigate the performance of macrolide antibiotics for the treatment of Mycoplasma pneumoniae pneumonia (MPP) in children with or without…

Date: 2026-05-18

Clinical utility of an evolving cholestasis gene panel in 10,000 children and adults

Abstract: Cholestasis has diverse causes, with genetic factors playing a key role. Diagnosis is challenging due to varied presentations and overlapping genetic conditions.…

Date: 2026-05-18

Resveratrol ameliorates intrahepatic cholestasis of pregnancy by modulating the gut-liver axis and FXR-mediated bile acid homeostasis

Abstract: Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder with limited treatment options. This study investigated the therapeutic potential of resveratrol (RES)…

Date: 2026-05-18

Probabilistic mapping of lymph node metastasis in epithelial ovarian cancer: a retrospective cohort study using Bayesian network analysis

Abstract: To characterize the anatomical distribution, potential metastatic pathways, and clinical factors associated with lymph node metastasis (LNM) in epithelial ovarian cancer…

Date: 2026-05-18

Integrated model of Student Standardized Patients and peer assessment enhances SOAP note proficiency in obstetrics and gynecology residency

Abstract: To assess the efficacy of an integrated training model that incorporates Students as Standardized Patients (SSPs) alongside structured peer assessment in enhancing SOAP…

Date: 2026-05-18