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Neoadjuvant FinHer regimen in patients with HER2-positive breast cancer: a retrospective audit

Abstract: The role of trastuzumab in the neoadjuvant setting has been established by multiple large randomized trials. However, there are limited data on the efficacy and survival…

Date: 2026-05-18

A novel nutritional index for predicting stroke-heart syndrome and clinical outcomes after endovascular treatment

Abstract: Metabolic-nutritional reserves influence stroke outcomes, but their role in large vessel occlusion acute ischemic stroke (LVO-AIS) treated with endovascular thrombectomy…

Date: 2026-05-18

Complete revascularization and heart failure risk in acute coronary syndrome across the ejection fraction spectrum: focus on LVEF-dependent effects

Abstract: To investigate the impact of complete revascularization (CR) versus incomplete revascularization (ICR) on the composite outcome of first hospitalization for heart…

Date: 2026-05-18

Association of the single-point insulin sensitivity estimator with arterial stiffness: a cross-sectional analysis

Abstract: Arterial stiffness is an early marker of vascular damage and cardiovascular risk. SPISE is a simple insulin-free surrogate of insulin sensitivity, but its association…

Date: 2026-05-18

Associations of novel visceral obesity indices (METS-VF and BRI) with dementia: the role of metabolic mediators and genetic susceptibility

Abstract: Visceral obesity-related indices may capture metabolically adverse adiposity more effectively than conventional obesity measures, but their comparative associations with…

Date: 2026-05-18

Association of systemic inflammation response index and triglyceride-glucose index with the severity of coronary artery stenosis in elderly patients: a retrospective cross-sectional study

Abstract: Atherosclerosis is significantly influenced by chronic inflammation and insulin resistance (IR). This study aims to explore the effects of the Systemic Inflammation…

Date: 2026-05-18

Development and application of an evidence-based three-dimensional, four-phase discharge preparation plan for type 2 diabetes patients

Abstract: To develop an evidence-based “three-dimensional integrated” four-stage discharge preparation plan for patients with type 2 diabetes mellitus (T2DM), and to investigate…

Date: 2026-05-15

Development and external validation of an interpretable machine learning model for diagnosing coronary heart disease in patients with type 2 diabetes and MASLD

Abstract: Patients with type 2 diabetes mellitus (T2DM) and metabolic dysfunction-associated steatotic liver disease (MASLD) face substantially elevated coronary heart disease…

Date: 2026-05-15

Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio is associated with cardiovascular outcomes after percutaneous coronary intervention in patients with type 2 diabetes

Abstract: The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is a novel, reliable indicator of dyslipidemia. However, its…

Date: 2026-05-15

Real-world effectiveness and safety of 200 mg abrocitinib initiation in Chinese adults with moderate-to-severe atopic dermatitis: a retrospective study

Abstract: Abrocitinib, a Janus kinase (JAK) inhibitor approved for moderate-to-severe atopic dermatitis (AD), has demonstrated efficacy at 100 mg in randomized controlled trials.…

Date: 2026-05-15