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Development and validation of a machine learning model for predicting postherpetic neuralgia risk

Abstract: Postherpetic neuralgia (PHN) is a debilitating complication of herpes zoster (HZ), and early identification of high-risk patients is crucial for timely intervention.…

Date: 2026-04-16

Identification and validation of druggable targets for cataract using mendelian randomization: functional insights from multi-omics and an oxidative stress model

Abstract: To identify druggable genes associated with cataract and investigate their functional roles under oxidative stress, thereby providing potential therapeutic targets.…

Date: 2026-04-16

Understanding perceptions of ophthalmology residents on pursuing a uveitis fellowship

Abstract: To investigate factors influencing the decision of ophthalmology residents in the United States to pursue a uveitis fellowship. A cross-sectional survey, with…

Date: 2026-04-16

Development and validation of a predictive nomogram for response to biologics and targeted therapy in Crohn’s disease: a retrospective cohort study

Abstract: Biologics and targeted therapies are a first-line treatment option for individuals with Crohn’s disease (CD). Nevertheless, clinical remission rates vary considerably…

Date: 2026-04-16

Stroke progression index as a dynamic metric is associated with functional outcome in progressive ischemic stroke with large vessel occlusion

Abstract: Current evaluation of progressive ischemic stroke (PIS) with large vessel occlusion (LVO) relies on static clinical or imaging measures and lacks quantitative assessment…

Date: 2026-04-16

Novel perspectives on the rare hemophagocytic lymphohistiocytosis: insights from a multi-center retrospective cohort

Abstract: Hemophagocytic syndrome, also known as hemophagocytic lymphohistiocytosis (HLH), is a rare clinical disease that is highly challenging to diagnose, has a low long-term…

Date: 2026-04-15

ANCA-associated vasculitis is associated with an increased risk of cardiac and vascular morbidity: results of a large-scale propensity-matched global retrospective cohort study

Abstract: Despite significantly improved therapies in recent years, long-term morbidity and mortality in ANCA-associated vasculitis (AAV) remain high. The leading causes of death…

Date: 2026-04-15

Respiratory ventilation modes in selective ophthalmic arterial chemotherapy for pediatric retinoblastoma under general anesthesia

Abstract: To determine the optimal ventilation strategy for pediatric patients with retinoblastoma undergoing selective ophthalmic arterial chemotherapy (SOAC) by comparing the…

Date: 2026-04-15

Prolonged anesthesia duration is associated with postoperative thyroid hormone reduction in pediatric surgical patients: a retrospective cohort study

Abstract: Postoperative reduction of thyroid hormones (TH), particularly triiodothyronine (T3), is frequently observed but poorly characterized in pediatric surgical patients.…

Date: 2026-04-15

Sleep quality as a mediator between perceived stress and dry eye severity among Chinese nurses

Abstract: This study aims to investigate the prevalence and influencing factors of dry eye among Chinese nurses, and to explore the relationship between nurses’ perceived stress,…

Date: 2026-04-15