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Association of the glucose metabolism continuum (fasting plasma glucose/HbA1c) with tear-film stability and secretion: ocular surface evidence across non-diabetes, prediabetes, and diabetes

Abstract: Whether gradations in glycemia across non-diabetes, prediabetes, and diabetes relate to tear?film homeostasis and dry eye disease (DED) remains uncertain, and…

Date: 2026-04-13

Unveiling the non-linear synergistic effects of smoking and aging on cataract-AMD comorbidity: an explainable artificial intelligence approach

Abstract: The comorbidity of cataract and age-related macular degeneration (AMD) poses a significant public health burden. Traditional linear statistical models often fail to…

Date: 2026-04-13

Preoperative information needs and preferences of refractive surgery patients: a discrete choice experiment

Abstract: Individualized preoperative information can enhance patient satisfaction. However, existing studies have methodological limitations, largely adopting a healthcare…

Date: 2026-04-13

Acute infection with the U.S. isolate of Theileria orientalis genotype Ikeda is associated with decreased hematocrit and erythrocyte counts in experimentally infected cattle

Abstract: The emergence of the tick-borne Ikeda genotype of Theileria orientalis poses a significant threat to the U.S. cattle industry. Although information has been gathered on…

Date: 2026-04-10

Long-term outcomes of co-administration of CD19 and CD22 CAR-T cell therapy in pediatric patients with relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia

Abstract: Despite initial responses, resistance to tyrosine kinase inhibitors (TKIs) and disease relapse remain major challenges in patients with Philadelphia chromosome-positive…

Date: 2026-04-10

Accelerated response and reduced chemotherapy with ruxolitinib-based regimen therapy in pediatric hemophagocytic lymphohistiocytosis: a retrospective comparison with HLH-94 regimen

Abstract: To compare the efficacy of a Ruxolitinib-based regimen versus the conventional HLH-94 protocol in children with newly diagnosed hemophagocytic lymphohistiocytosis (HLH).…

Date: 2026-03-26

Value, development challenges, and strategies for gaining internal endorsement of digitally connected subcutaneous drug delivery devices: a survey of pharmaceutical stakeholders

Abstract: Connected drug delivery devices such as combination products that integrate traditional drug delivery systems with digital connectivity features represent an opportunity…

Date: 2026-03-26

Life Story Work as an inclusive methodology to explore identity in intellectual disability

Abstract: This study explores how young people with intellectual disability (ID) construct and negotiate their identities through life stories, adopting a narrative perspective…

Date: 2026-03-26

Development and validation of a risk prediction model of delayed onset of lactogenesis among mothers with gestational diabetes mellitus: a prospective multicenter study

Abstract: The aim of this study is to develop and validate a prediction model of delayed onset of lactogenesis among mothers with gestational diabetes mellitus. This was a…

Date: 2026-03-26

The development and validation of a machine learning algorithm for identifying lateral lymph nodes skip metastasis in papillary thyroid cancer

Abstract: Skip metastasis from papillary thyroid cancer (PTC) is often unpredictable and characterized by lateral lymph node metastasis without central lymph node metastasis. Our…

Date: 2026-03-26