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Adiponectin and phase angle in the assessment of sarcopenia in Crohn’s disease: beyond muscle mass

Abstract: Sarcopenia is a common and clinically relevant complication of Crohn’s disease (CD), reflecting the cross-link among chronic inflammation, malnutrition, and metabolic…

Date: 2026-04-23

Clinical experience using trofinetide in Rett syndrome and related MECP2 diagnosis at the children’s hospital of Philadelphia post approval

Abstract: Rett syndrome (RTT) is a rare neurodevelopmental disorder primarily caused by pathogenic variants in the MECP2 gene. Trofinetide (Daybue) became the first FDA-approved…

Date: 2026-04-23

B-cell subset changes and clinical predictors of telitacicept response in SLE patients with antiphospholipid antibody positivity: a prospective observational cohort study

Abstract: To characterize the dynamic changes in B-cell subsets in Systemic lupus erythematosus (SLE) patients with antiphospholipid antibody (aPL) positivity treated with…

Date: 2026-04-23

Differential spleen immune signatures and germinal center responses during acute infection with Orientia tsutsugamushi Karp versus Gilliam strains

Abstract: Scrub typhus is an emerging and neglected tropical disease caused by Orientia tsutsugamushi ( Ot ). Immunity in scrub typhus patients is known to be short-lived;…

Date: 2026-04-23

Ethical decision-making confidence among nurse leaders: a mixed-methods study of determinants and ethical implications

Abstract: In today’s complex healthcare environment, ethical decision-making confidence (EDMC) among nurse leaders plays a pivotal role in ensuring ethically sound nursing…

Date: 2026-04-23

Delayed type I interferon response and the subsequent out-of-sequence cytokine signal inhibit T cell induction in non-surviving Ebola virus-infected patients

Abstract: While there is evidence that Ebola virus (EBOV) antagonizes the antiviral type I interferon (IFN-I) response, the role of IFN-I for EBOV disease remains controversial,…

Date: 2026-04-23

Status Quo analysis of an exercise therapy care model in pediatric oncology during acute therapy: perspectives from patients, parents, siblings, and staff

Abstract: In oncological pediatrics, exercise therapy is still not part of regular medical care in Germany and exercise therapy projects are currently financed by charity…

Date: 2026-04-22

A comparative study of the impact of lineal relatives versus collateral relatives donor on prognosis in haplo-HSCT for aplastic anemia

Abstract: To investigate the impact of Lineal and Collateral donors on the prognosis of recipients in haplo-HSCT for AA among relatives. A retrospective analysis of data from AA…

Date: 2026-04-22

Plasma expression of long non-coding RNA GAS5 and its prognostic significance in newly diagnosed multiple myeloma

Abstract: Long non-coding RNAs (lncRNAs) participate in pathogenesis, progression and therapy resistance in multiple myeloma (MM). Growth Arrest-Specific 5 ( GAS5 ) is a lncRNA…

Date: 2026-04-22

Clinical and immunological analysis of letermovir for preventing cytomegalovirus infection in children after hematopoietic stem cell transplantation

Abstract: The present study aimed to analyze the efficacy and safety of letermovir for preventing cytomegalovirus (CMV) infection and its impact on immune reconstitution in…

Date: 2026-04-22